MK-4827 racemate (Niraparib racemate) is a selective inhibitor of PARP1/2 with IC50 of 3.8 nM/2.1 nM; >330-fold selective against PARP3, V-PARP and Tank1.
MK-4827 Racemate
Catalog No.: GC17052Purity:>98%
selective inhibitor of PARP1/PARP2
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1038915-75-1
5mgIn Stock
$106.00
1
10mgIn Stock
$164.00
1
50mgIn Stock
$572.00
1
100mgIn Stock
$974.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $106.00 | In Stock | 1 | |
| 10mg | $164.00 | In Stock | 1 | |
| 50mg | $572.00 | In Stock | 1 | |
| 100mg | $974.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
1038915-75-1
Chemical Name
2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid
SMILES
N=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C(C4CCCNC4)C=C3
Molecular Formula
C19H20N4O
Molecular Weight
320.39
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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