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TH 5427 hydrochloride

Catalog No.GC50490

Potent NUDT5 inhibitor

Products are for research use only. Not for human use. We do not sell to patients.

TH 5427 hydrochloride Chemical Structure

Cas No.: 2253744-57-7

Size Price Stock Qty
10 mg
$243.00
In stock
50 mg
$1,017.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Potent nudix hydrolase 5 (NUDT5) inhibitor (IC50 = 29 nM). Displays >650-fold selectivity for NUDT5 over MTH1. Inhibits ATP synthesis, chromatin remodeling, gene expression and proliferation in progestin-treated breast cancer cells in vitro.

Page et al (2018) Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat.Commun. 9 250 PMID:29343827

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Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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