Destruxin A (Synonyms: SB 242533) |
| Catalog No.GC19426 |
A cyclic hexadepsipeptide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6686-70-0
Sample solution is provided at 25 µL, 10mM.
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Destruxin A is a cyclic hexadepsipeptide mycotoxin first isolated from O. destructor and commonly found in entomopathogenic fungi.1 It has insecticidal activity by affecting diverse pathways, including those related to immune response, calcium signaling, and development.2,3
References:
1. Pedras, M., Zaharia, L.I., and Ward, D.E. The destruxins: Synthesis, biosynthesis, biotransformation, and biological activity Phytochemistry 59(6), 579-596 (2002).
2. Han, P., Jin, F., Dong, X., et al. Transcript and protein profiling analysis of the Destruxin A-induced response in larvae of Plutella xylostella PLoS One 8(4), (2013).
3. Pal, S., St.Leger, R.J., and Wu, L.P. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster J.Biol.Chem. 282(12), 8969-8977 (2007).
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