Cardiovascular
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Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Research Areas
- Acute Phase Reactants(15)
- Angina(14)
- Arrhythmia(82)
- Atherosclerosis(88)
- Chronic Kidney Disease(18)
- Coagulation & Hemostasis(124)
- Coronary Artery Disease(7)
- Diabetic Nephropathy(8)
- Endothelium(33)
- Erythrocytes & Hemoglobin(49)
- Heart Failure(33)
- Hypertension(162)
- Hypotension(24)
- Lipoproteins(61)
- Myocardial Contractility(33)
- Myocardial Hypertrophy(21)
- Myocardial Infarction(61)
- Others(1)
- Serum Proteins(11)
- Smooth Muscle Cells(36)
- Storage & Transport(6)
- Stroke(48)
- Thrombosis(52)
- Vasoconstriction(59)
- Vasodilation(141)
- Cardiogenesis
- Cardiomyopathy(5)
- Cholesterol Metabolism(44)
Products Related to Cardiovascular(821)
- GC52019Norpropranolol (hydrochloride)CAS: 62618-09-1Purity: >98.00%
An active metabolite of propranolol
- GC52023Alfuzosin-d7CAS: 1133386-93-2Purity: >99.00%
An internal standard for the quantification of alfuzosin
- GC52034QuinaprilatCAS: 82768-85-2Purity: >90.00%
Quinaprilat is an orally active non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril.
- GC52045N-desmethyl AzelastineCAS: 47491-38-3Purity: >98.00%
N-desmethyl Azelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours.
- GC520483-hydroxy-4-Methoxyphenethylamine (hydrochloride)CAS: 645-33-0Purity: >98.00%
3-hydroxy-4-Methoxyphenethylamine (hydrochloride) is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase.
- GC52051DesglymidodrineCAS: 3600-87-1Purity: >98.00%
Desglymidodrine (ST 1059), the active metabolite of Midodrine, is a selective α1-adrenoceptor agonist.
- GC52058AcebutololCAS: 37517-30-9Purity: >99.50%
Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist.
- GC520654-Methoxyphenyl-β-D-GlucopyranosideCAS: 6032-32-2Purity: >98.00%
An aryl glycoside with ice recrystallization inhibitory activity
- GC52069N-Methyl-4-pyridone-5-carboxamideCAS: 769-49-3Purity: >98.00%
A metabolite of nicotinic acid and a uremic toxin
- GC52084YSK05CAS: 1318793-78-0Purity: >90.00%
YSK05 is a pH-sensitive cationic lipid. YSK05 improves the intracellular trafficking of non-viral vectors. YSK05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK05 overcomes the suppression of endosomal escape by PEGylation. YSK05 effectively enhances siRNA delivery both in vitro and in vivo.
- GC52112Stercobilinogen (technical grade)CAS: 17095-63-5Purity: >98.00%
A metabolite of bilirubin and a precursor in the biosynthesis of stercobilin
- GC521222’-Deoxyadenosine-5’-diphosphate (sodium salt)CAS: 402491-35-4Purity: >95.00%
A nucleotide diphosphate
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC50196 | Simvastatin - d6 | 1002347-71-8 | >99.50% | |
Deuterated simvastatin | ||||
| GC52005 | Triazolomethylindole-3-acetic Acid | 177270-91-6 | >95.00% | |
A metabolite of rizatriptan | ||||
| GC52006 | CB-096 | 108883-90-5 | >98.00% | |
An inhibitor of RAN translation | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52011 | Stearic Acid glycidyl ester | 7460-84-6 | >95.00% | |
An esterified form of stearic acid | ||||
| GC52019 | Norpropranolol (hydrochloride) | 62618-09-1 | >98.00% | |
An active metabolite of propranolol | ||||
| GC52023 | Alfuzosin-d7 | 1133386-93-2 | >99.00% | |
An internal standard for the quantification of alfuzosin | ||||
| GC52034 | Quinaprilat | 82768-85-2 | >90.00% | |
Quinaprilat is an orally active non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril. | ||||
| GC52035 | Esmolol Acid (hydrochloride) | 83356-60-9 | >98.00% | |
An active metabolite of esmolol | ||||
| GC52045 | N-desmethyl Azelastine | 47491-38-3 | >98.00% | |
N-desmethyl Azelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. | ||||
| GC52048 | 3-hydroxy-4-Methoxyphenethylamine (hydrochloride) | 645-33-0 | >98.00% | |
3-hydroxy-4-Methoxyphenethylamine (hydrochloride) is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase. | ||||
| GC52051 | Desglymidodrine | 3600-87-1 | >98.00% | |
Desglymidodrine (ST 1059), the active metabolite of Midodrine, is a selective α1-adrenoceptor agonist. | ||||
| GC52052 | Dofetilide N-oxide | 144449-71-8 | >98.00% | |
| GC52058 | Acebutolol | 37517-30-9 | >99.50% | |
Acebutolol is an orally active β1 adrenergic receptor (β1AR) antagonist. | ||||
| GC52065 | 4-Methoxyphenyl-β-D-Glucopyranoside | 6032-32-2 | >98.00% | |
An aryl glycoside with ice recrystallization inhibitory activity | ||||
| GC52069 | N-Methyl-4-pyridone-5-carboxamide | 769-49-3 | >98.00% | |
A metabolite of nicotinic acid and a uremic toxin | ||||
| GC52084 | YSK05 | 1318793-78-0 | >90.00% | |
YSK05 is a pH-sensitive cationic lipid. YSK05 improves the intracellular trafficking of non-viral vectors. YSK05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK05 overcomes the suppression of endosomal escape by PEGylation. YSK05 effectively enhances siRNA delivery both in vitro and in vivo. | ||||
| GC52112 | Stercobilinogen (technical grade) | 17095-63-5 | >98.00% | |
A metabolite of bilirubin and a precursor in the biosynthesis of stercobilin | ||||
| GC52122 | 2’-Deoxyadenosine-5’-diphosphate (sodium salt) | 402491-35-4 | >95.00% | |
A nucleotide diphosphate | ||||
| GC52125 | T-1095 | 209746-59-8 | >98.00% | |
T-1095 is a selective and orally active Na+-glucose cotransporter (SGLT) inhibitor with IC50s of 22.8 ?M and 2.3 ?M for human SGLT1 and SGLT2, respectively. | ||||
| GC52132 | N-desmethyl Diltiazem (hydrochloride) | 130606-60-9 | >90.00% | |
| GC52145 | Bradykinin (human, mouse, rat, bovine) (acetate) | 6846-03-3 | >98.00% | |
| GC52149 | 306-O12B | 2566523-06-4 | >98.00% | |
306-O12B is an ionizable cationic lipid used to generate lipid nanoparticles (LNPs). | ||||
| GC52150 | Velaresol | 77858-21-0 | >98.00% | |