GLPBio

COX

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products Related to COX(306)

  • GC36828 structure
    GC36828Oxaprozin D4
    Purity: >98%

    Oxaprozin D4 (Wy-21743 D4) is the deuterium labeled Oxaprozin, which is a non-steroidal anti-inflammatory agent (NSAID).

  • GC36852 structure
    GC36852Parecoxib
    CAS: 198470-84-7
    Purity: >98.00%

    Parecoxib (SC 69124) is a highly selective?and orally active COX-2 inhibitor, the prodrug of Valdecoxib.

  • GC38015 structure
    GC38015Eicosatetraynoic acid
    CAS: 1191-85-1
    Purity: >98%

    A nonspecific inhibitor of cyclooxygenases and lipoxygenases

  • GC38066 structure
    GC38066Mavacoxib
    CAS: 170569-88-7
    Purity: >98.00%

    Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID).

  • GC38151 structure
    GC38151Roburic acid
    CAS: 6812-81-3
    Purity: >99.00%
  • GC38184 structure
    GC38184Dehydrodiisoeugenol
    CAS: 2680-81-1
    Purity: >98.00%

    Dehydrodiisoeugenol (DEH) is a representative and major benzofuran-type neolignan found in Myristica fragrans Houtt, possessing antibacterial, anti-inflammatory, anticancer, and antioxidant properties.

  • GC38196 structure
    GC38196Licofelone
    CAS: 156897-06-2
    Purity: >98%

    A dual inhibitor of COX1/COX2 and 5LO

  • GC38198 structure
    GC38198Revaprazan hydrochloride
    CAS: 178307-42-1
    Purity: >98.00%

    Revaprazan hydrochloride is a novel acid pump antagonist (APA).

  • GC38224 structure
    GC38224Crocin II
    CAS: 55750-84-0
    Purity: >98.00%
  • GC38431 structure
    GC38431Dehydroevodiamine
    CAS: 67909-49-3
    Purity: >98.00%

    Dehydroevodiamine is a major bioactive quinazoline alkaloid isolated from Evodiae Fructus, has an antiarrhythmic effect in guinea-pig ventricular myocytes.

  • GC38616 structure
    GC38616Hamaudol
    CAS: 735-46-6
    Purity: >98%

    Hamaudol is a chromone isolated from Saposhnikovia divaricata.

  • GC38678 structure
    GC38678Ethyl Caffeate
    CAS: 102-37-4
    Purity: >98.50%

    Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa.

  • GC39013 structure
    GC39013FPL 62064
    CAS: 103141-09-9
    Purity: >98.00%

    FPL 62064 is a potent 5-lipoxygenase (5-LOX) and COX dual inhibitor, with IC50 values of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase (cyclooxygenase), respectively.

  • GC39040 structure
    GC39040Taraxerol acetate
    CAS: 2189-80-2
    Purity: >98%

    Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis.

  • GC39134 structure
    GC39134Isofraxidin
    CAS: 486-21-5
    Purity: >98.00%

    Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells.

  • GC39307 structure
    GC393074-Methylamino antipyrine
    CAS: 519-98-2
    Purity: >98.00%

    4-Methylamino antipyrine is an active metabolite of Metamizole.

  • GC39534 structure
    GC39534Isoxicam
    CAS: 34552-84-6
    Purity: >98.00%

    Isoxicam is an orally active, long-acting, non-steroidal anti-inflammatory agent for the research of arthritis.

  • GC39583 structure
    GC39583Nimesulide D5
    CAS: 1330180-22-7
    Purity: >98%

    An internal standard for the quantification of nimesulide

  • GC40065 structure
    GC40065Meloxicam-d3
    CAS: 942047-63-4
    Purity: >99.00%

    Meloxicam-d3 is intended for use as an internal standard for the quantification of meloxicam by GC- or LC-MS.

  • GC40227 structure
    GC40227Indomethacin-d4
    CAS: 87377-08-0
    Purity: >99.00%

    Indomethacin-d4 is intended for use as an internal standard for the quantification of indomethacin by GC- or LC-MS.

  • GC40262 structure
    GC40262α-Humulene
    CAS: 6753-98-6
    Purity: >95.00%

    α-Humulene is a sesquiterpene found in essential oils of various plant species with an IC 50 value of 15μg/ml for anti-inflammatory activities.

  • GC40352 structure
    GC40352Cafestol
    CAS: 469-83-0
    Purity: >98.00%

    Cafestol, one of the major components of coffee, is a coffee-specific diterpene form and an inhibitor of ERK2.

  • GC40565 structure
    GC40565Feprazone
    CAS: 30748-29-9
    Purity: >98.00%

    Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1.

  • GC40651 structure
    GC40651Oxyphenbutazone
    CAS: 129-20-4
    Purity: >99.00%

    Oxyphenbutazone is a metabolite of phenylbutazone.