Eicosatetraynoic acid |
| Catalog No.GC38015 |
A nonspecific inhibitor of cyclooxygenases and lipoxygenases
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1191-85-1
Sample solution is provided at 25 µL, 10mM.
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Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively)[1]. Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 µM[2].
[1]. HammarstrÖm S, et al. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. Biochim Biophys Acta. 1977 Jun 22;487(3):517-9. [2]. Kliewer SA, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9.
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