GLPBio

TRP Channel

TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.

Products Related to TRP Channel(184)

  • GC40696 structure
    GC40696(R)-(+)-Pulegone
    CAS: 89-82-7
    Purity: >98.00%

    (R)-(+)-Pulegone, the major chemical constituent of Calamintha nepeta (L.

  • GC40808 structure
    GC40808(+)-Menthol
    CAS: 15356-60-2
    Purity: >98.00%

    (+)-Menthol is a monoterpene alcohol that has been found in Cannabis and has antifungal activity.

  • GC40860 structure
    GC40860AC1903
    CAS: 831234-13-0
    Purity: >99.50%

    AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM).

  • GC43884 structure
    GC43884Hyperforin (dicyclohexylammonium salt)
    CAS: 238074-03-8
    Purity: >98.00%

    Hyperforin (dicyclohexylammonium salt) is a main active constituent of St. John's wort . Hyperforin activates the transient receptor potential canonical 6 (TRPC6) channels.

  • GC44075 structure
    GC44075Linopirdine
    CAS: 105431-72-9
    Purity: >98.50%

    Linopirdine is an enhancer of the stimulus-evoked but not basal release of several neurotransmitters, including acetylcholine, dopamine, serotonin, and glutamate.

  • GC44816 structure
    GC44816Resolvin D2
    CAS: 810668-37-2
    Purity: >95.00%

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

  • GC45907 structure
    GC45907RN-9893 (hydrochloride)
    CAS: 2109450-40-8
    Purity: >98.00%

    A TRPV4 antagonist

  • GC46199 structure
    GC46199PF-05105679
    CAS: 1398583-31-7
    Purity: >98.00%

    A TRPM8 antagonist

  • GC50058 structure
    GC50058AMG 21629
    CAS: 939040-79-6
    Purity: >98%

    Potent and selective TRPV1 antagonist

  • GC50115 structure
    GC50115ASP 7663
    CAS: 1190217-35-6
    Purity: >99.00%

    Selective TRPA1 activator

  • GC50188 structure
    GC50188CIM 0216
    CAS: 1031496-06-6
    Purity: >99.50%

    Selective TRPM3 agonist

  • GC50261 structure
    GC50261A 425619
    CAS: 581809-67-8
    Purity: >98%

    Potent TRPV1 antagonist

  • GC50268 structure
    GC50268M 084 hydrochloride
    Purity: >98%

    TRPC4/5 channel blocker; antidepressant and anxiolytic

  • GC50475 structure
    GC50475AM 12
    CAS: 2387510-84-9
    Purity: >98%

    TRPC5 inhibitor

  • GC50557 structure
    GC50557CBA
    CAS: 351424-20-9
    Purity: >98.00%

    CBA (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM.

  • GC50590 structure
    GC50590TRPC6-PAM-C20
    CAS: 667427-75-0
    Purity: >98%

    Selective TRPC6 positive allosteric modulator

  • GC50617 structure
    GC50617BTD
    CAS: 896684-04-1
    Purity: >98%

    Selective TRPC5 activator

  • GC50640 structure
    GC50640OptoBI-1
    CAS: 2415272-11-4
    Purity: >98%

    Photoswitchable TRPC3/6/7 agonist

  • GC50641 structure
    GC50641IA-Alkyne
    CAS: 930800-38-7
    Purity: >99.00%

    Broad spectrum cysteine reactive probe

  • GC50667 structure
    GC50667SET 2
    CAS: 2313525-20-9
    Purity: >98.00%
  • GC50670 structure
    GC50670D-GsMTx4
    Purity: >98.00%
  • GC60542 structure
    GC605428-Gingerol
    CAS: 23513-08-8
    Purity: >99.00%

    A natural TRPV1 agonist

  • GC61792 structure
    GC61792Cyclic ADP-ribose ammonium
    Purity: >99.00%
  • GC62179 structure
    GC62179Cyclic ADP-ribose
    CAS: 119340-53-3
    Purity: >95.00%

    Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase.