TRPC6-PAM-C20 |
| Catalog No.GC50590 |
Selective TRPC6 positive allosteric modulator
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 667427-75-0
Sample solution is provided at 25 µL, 10mM.
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Selective TRPC6 positive allosteric modulator. Selectively activates TRPC6 over other TRP channels. Also activates TRPA1. Induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50 = 2.37 μM). Potentiates OAG (1-oleoyl-1-acetyl-sn-glycerol)-induced Ca2+ influx in human platelets, and enhances OAG-induced platelet aggregation.
Häfner et al (2019) Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels. Cell Calcium 78 26 PMID:30594060
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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