PKC
PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.
Products Related to PKC(146)
- GC73183CDK8-IN-12CAS: 2613307-67-6Purity: >99.00%
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM.
- GC73968Pim-1 kinase inhibitor 8CAS: 916038-47-6Purity: >99.00%
Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM.
- GC74417PKCθ pseudosubstrate peptide inhibitor,myristoylated TFAPurity: >98.00%
PKCθ pseudosubstrate peptide inhibitor, myristoylated TFA is a synthetic peptide that can be used to study the mechanism of action of PKCθ.
- GC74419N-myristoyl-RKRTLRRLCAS: 152246-40-7Purity: >99.00%
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates.
- GC79187TAT-Epsilon-V1-2 TFAPurity: >99.50%
TAT-Epsilon-V1-2 TFA is a cell-permeable PKCε peptide inhibitor.
- GC81672Senkyunolide BCAS: 93236-67-0Purity: >98%
Senkyunolide B is a phthalide found in Angelica sinensis.
- GC81880OSU-2S TFAPurity: >98.00%
OSU-2S TFA is a non-immunosuppressive derivative of Fingolimod hydrochloride (FTY720).
- GC90543EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)Purity: >95.00%
A PKC inhibitor
- GC11499Enzastaurin (LY317615)CAS: 170364-57-5Purity: >99.50%
Enzastaurin (LY317615) is an ATP-competitive and selective inhibitor of PKCβ with an IC 50 value of 6nM.
- GC15431GF 109203X (Bisindolylmaleimide I)CAS: 133052-90-1Purity: >99.00%
GF 109203X is a selective inhibitor of protein kinase C, selective for the α and β1 isoforms with IC 50 values of 0.0084, 0.0180, 0.210, 0.132, and 5.8μM for α, β1, δ, ε and ζ isoforms of protein kinase C respectively.
- GC15520Sotrastaurin (AEB071)CAS: 425637-18-9Purity: >99.50%
Sotrastaurin (AEB071) is a potent and orally-active pan-protein kinase C (PKC) inhibitor, with Ki values of 0.22nM, 0.64nM, 0.95nM, 1.8nM, 2.1nM and 3.2nM for PKCθ, PKCβ, PKCα, PKCη, PKCδ and PKCε, respectively.
- GC14701Zoledronic AcidCAS: 118072-93-8Purity: >99.00%
Zoledronic Acid is a third-generation nitrogen-containing bisphosphonate bone resorption inhibitor.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC72185 | SAMβA TFA | - | >98.00% | |
SAMβA TFA is conjugated to the cell permeable peptide TAT47-57. | ||||
| GC72880 | PS432 | 2083630-26-4 | >99.00% | |
PS432 is a PKC inhibitor with IC50s of 16.9 μM (PKCι) and 18.5 μM (PKCζ), respectively. | ||||
| GC73183 | CDK8-IN-12 | 2613307-67-6 | >99.00% | |
CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM. | ||||
| GC73968 | Pim-1 kinase inhibitor 8 | 916038-47-6 | >99.00% | |
Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM. | ||||
| GC74326 | MPSD TFA | - | >98.00% | |
MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD. | ||||
| GC74417 | PKCθ pseudosubstrate peptide inhibitor,myristoylated TFA | - | >98.00% | |
PKCθ pseudosubstrate peptide inhibitor, myristoylated TFA is a synthetic peptide that can be used to study the mechanism of action of PKCθ. | ||||
| GC74419 | N-myristoyl-RKRTLRRL | 152246-40-7 | >99.00% | |
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. | ||||
| GC79186 | (1S,4R)-CC-90005 | - | >99.50% | |
(1S,4R)-CC-90005 is the (1S,4R)-enantiomer of CC-90005. | ||||
| GC79187 | TAT-Epsilon-V1-2 TFA | - | >99.50% | |
TAT-Epsilon-V1-2 TFA is a cell-permeable PKCε peptide inhibitor. | ||||
| GC79707 | ST1072 | 1402703-50-7 | >98% | |
ST1072 is an inhibitor of CerS4 and CerS6. | ||||
| GC81672 | Senkyunolide B | 93236-67-0 | >98% | |
Senkyunolide B is a phthalide found in Angelica sinensis. | ||||
| GC81880 | OSU-2S TFA | - | >98.00% | |
OSU-2S TFA is a non-immunosuppressive derivative of Fingolimod hydrochloride (FTY720). | ||||
| GC90543 | EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt) | - | >95.00% | |
A PKC inhibitor | ||||
| GN10336 | Daphnetin | 486-35-1 | >99.00% | |
| GN10444 | 12-O-tetradecanoyl phorbol-13-acetate | 16561-29-8 | >98.00% | |
A PKC activator | ||||
| GN10463 | Chelerythrine | 34316-15-9 | >98% | |
| GC11499 | Enzastaurin (LY317615) | 170364-57-5 | >99.50% | |
Enzastaurin (LY317615) is an ATP-competitive and selective inhibitor of PKCβ with an IC 50 value of 6nM. | ||||
| GC15281 | K-252c | 85753-43-1 | >99.00% | |
Protein kinase inhibitor | ||||
| GC15420 | ICP 103 | - | >98% | |
Protein kinase inhibitor | ||||
| GC15431 | GF 109203X (Bisindolylmaleimide I) | 133052-90-1 | >99.00% | |
GF 109203X is a selective inhibitor of protein kinase C, selective for the α and β1 isoforms with IC 50 values of 0.0084, 0.0180, 0.210, 0.132, and 5.8μM for α, β1, δ, ε and ζ isoforms of protein kinase C respectively. | ||||
| GC15520 | Sotrastaurin (AEB071) | 425637-18-9 | >99.50% | |
Sotrastaurin (AEB071) is a potent and orally-active pan-protein kinase C (PKC) inhibitor, with Ki values of 0.22nM, 0.64nM, 0.95nM, 1.8nM, 2.1nM and 3.2nM for PKCθ, PKCβ, PKCα, PKCη, PKCδ and PKCε, respectively. | ||||
| GC16907 | Go 6983 | 133053-19-7 | >99.00% | |
Go 6983 is a pan-PKC inhibitor that acts on PKCα, PKCβ, PKCγ, PKCδ, andPKCμ with IC 50 values of 7nM, 7nM, 6nM, 10nM, and 20μM, respectively. | ||||
| GC14701 | Zoledronic Acid | 118072-93-8 | >99.00% | |
Zoledronic Acid is a third-generation nitrogen-containing bisphosphonate bone resorption inhibitor. | ||||
| GC16354 | Dequalinium Chloride | 522-51-0 | >98.00% | |
anti-tumor agent and PKC inhibitor | ||||