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Metabolism

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  1. Cat.No. Nom du produit Informations
  2. GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone 5β-Dihydroprogesterone  Chemical Structure
  3. GC49176 5β-Tetrahydrocortisol An endogenous metabolite of cortisol 5β-Tetrahydrocortisol  Chemical Structure
  4. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam  Chemical Structure
  5. GC49499 5(Z)-Dodecenoic Acid L'acide 5(Z)-dodécénoÏque est un métabolite endogène ayant des activités inhibitrices contre la COX-I et la COX-II. 5(Z)-Dodecenoic Acid  Chemical Structure
  6. GC18542 5,6-dihydro-5-Fluorouracil

    5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).

    5,6-dihydro-5-Fluorouracil  Chemical Structure
  7. GC18466 5,6-epoxy-13-cis Retinoic Acid 5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid. 5,6-epoxy-13-cis Retinoic Acid  Chemical Structure
  8. GC13319 5,8,11-Eicosatriynoic Acid nonselective inhibitor of lipoxygenases (12-LO) 5,8,11-Eicosatriynoic Acid  Chemical Structure
  9. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone  Chemical Structure
  10. GC63358 5-Aminosalicylic Acid-D3 hydrochloride 5-Aminosalicylic Acid-D3 hydrochloride  Chemical Structure
  11. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7  Chemical Structure
  12. GC49827 5-Androstenetriol An active metabolite of DHEA 5-Androstenetriol  Chemical Structure
  13. GC49877 5-bromo-3-indolyl-β-D-Galactopyranoside Le 5-bromo-3-indolyl-β-D-galactopyranoside (Bluo-Gal) est un substrat chromogène pour détecter l'activité bactérienne de la β-D-galactosidase. 5-bromo-3-indolyl-β-D-Galactopyranoside  Chemical Structure
  14. GC49655 5-hydroxy Buspirone A metabolite of buspirone 5-hydroxy Buspirone  Chemical Structure
  15. GC42546 5-hydroxy Diclofenac 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. 5-hydroxy Diclofenac  Chemical Structure
  16. GC49119 5-hydroxy Flunixin A metabolite of flunixin 5-hydroxy Flunixin  Chemical Structure
  17. GC49315 5-hydroxy Indomethacin A metabolite of indomethacin 5-hydroxy Indomethacin  Chemical Structure
  18. GC41312 5-hydroxy Omeprazole

    5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump.

    5-hydroxy Omeprazole  Chemical Structure
  19. GC12829 5-hydroxy Tryptophol Le 5-hydroxy tryptophol est un métabolite de la sérotonine chez les mammifères, agissant comme un marqueur de la consommation aiguë d'alcool. 5-hydroxy Tryptophol  Chemical Structure
  20. GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine. 5-hydroxy-6-methoxy (S)-Duloxetine  Chemical Structure
  21. GC42551 5-hydroxymethyl Tolterodine (formate) 5-hydroxymethyl Tolterodine is an active metabolite of the muscarinic acetylcholine receptor antagonists tolterodine and fesoterodine. 5-hydroxymethyl Tolterodine (formate)  Chemical Structure
  22. GN10241 5-Methoxypsoralen 5-Methoxypsoralen  Chemical Structure
  23. GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid 5-Methyltetrahydrofolic Acid (hydrate)  Chemical Structure
  24. GC41310 5-Octyl-α-ketoglutarate In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate  Chemical Structure
  25. GC46713 5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate) An intermediate in several biochemical pathways 5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)  Chemical Structure
  26. GC11101 5-R-Rivaroxaban 5-R-Rivaroxaban  Chemical Structure
  27. GC42586 6α-hydroxy Paclitaxel 6α-hydroxy Paclitaxel est un métabolite primaire du Paclitaxel. 6α-hydroxy Le paclitaxel conserve un effet dépendant du temps sur les polypeptides transporteurs d'anions organiques 1B1/SLCO1B1 (OATP1B1) avec une puissance d'inhibition similaire À celle du paclitaxel, alors qu'il n'a plus montré d'inhibition dépendante du temps de l'OATP1B3. 6α-hydroxy Paclitaxel peut être utilisé pour la recherche sur le cancer. 6α-hydroxy Paclitaxel  Chemical Structure
  28. GC49676 6β-hydroxy Budesonide A metabolite of budesonide 6β-hydroxy Budesonide  Chemical Structure
  29. GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone 6β-hydroxy Eplerenone  Chemical Structure
  30. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone  Chemical Structure
  31. GC19536 6'-Sialyllactose Sodium Salt 6'-Sialyllactose (sodium), un oligosaccharide prédominant du lait, réduit l'internalisation de Pseudomonas aeruginosa dans les pneumocytes humains. 6'-Sialyllactose Sodium Salt  Chemical Structure
  32. GC52056 6(Z),9(Z),12(Z),15(Z)-Hexadecatetraenoic Acid ethyl ester L'ester éthylique de l'acide 6(Z),9(Z),12(Z),15(Z)-hexadécatétraénoÏque est un n-1PUFA actif par voie orale. 6(Z),9(Z),12(Z),15(Z)-Hexadecatetraenoic Acid ethyl ester  Chemical Structure
  33. GC11864 6,7-dihydroxy Bergamottin potent inhibitor of CYP3A4 6,7-dihydroxy Bergamottin  Chemical Structure
  34. GC10868 6,7-Dimethyltetrahydropterin (hydrochloride) GTP cyclohydrolase I inhibitor 6,7-Dimethyltetrahydropterin (hydrochloride)  Chemical Structure
  35. GC10462 6-Aminonicotinamide Le 6-aminonicotinamide, un antimétabolite puissant du nicotinamide, est un inhibiteur compétitif de l'enzyme glucose-6-phosphate déshydrogénase (G6PD) dépendante du NADP (Ki =0,46 μM). Le 6-aminonicotinamide interfère avec la glycolyse, entraÎnant un épuisement de l'ATP et agit en synergie avec les médicaments de chimiothérapie réticulant l'ADN, tels que le cisplatine, pour tuer les cellules cancéreuses. 6-Aminonicotinamide  Chemical Structure
  36. GC46722 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) A β-glucuronidase chromogenic substrate 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt)  Chemical Structure
  37. GC18632 6-hydroxy Bexarotene 6-hydroxy Bexarotene is an oxidative metabolite of bexarotene , a high-affinity ligand for retinoid X receptors (RXRs). 6-hydroxy Bexarotene  Chemical Structure
  38. GC42580 6-hydroxy Chlorzoxazone

    6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.

    6-hydroxy Chlorzoxazone  Chemical Structure
  39. GC49183 6-hydroxy Etodolac A metabolite of etodolac 6-hydroxy Etodolac  Chemical Structure
  40. GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin . 6-hydroxy Warfarin  Chemical Structure
  41. GC49429 6-keto Lithocholic Acid A metabolite of lithocholic acid 6-keto Lithocholic Acid  Chemical Structure
  42. GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine 6-Methylmercaptopurine  Chemical Structure
  43. GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP 6-Methylmercaptopurine-d3  Chemical Structure
  44. GC18870 6-NBDG Le 6-NBDG est un analogue fluorescent du glucose, il peut être utilisé pour l'imagerie par fluorescence et la surveillance du transport et de l'absorption du glucose. 6-NBDG  Chemical Structure
  45. GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin 6-O-Demethyl Griseofulvin  Chemical Structure
  46. GC42584 6-O-desmethyl Donepezil 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil. 6-O-desmethyl Donepezil  Chemical Structure
  47. GC46726 6-O-Sulfo-β-cyclodextrin (sodium salt) A sulfated cyclodextrin 6-O-Sulfo-β-cyclodextrin (sodium salt)  Chemical Structure
  48. GC18335 6β-hydroxy Dexamethasone 6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. 6β-hydroxy Dexamethasone  Chemical Structure
  49. GC49206 7α-hydroxy Dehydroepiandrosterone An active metabolite of dehydroepiandrosterone 7α-hydroxy Dehydroepiandrosterone  Chemical Structure
  50. GC49298 7α-Thiomethylspironolactone A major metabolite of spironolactone 7α-Thiomethylspironolactone  Chemical Structure
  51. GC49391 7α-Thiospironolactone An active metabolite of spironolactone 7α-Thiospironolactone  Chemical Structure
  52. GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS. 7β-hydroxy Cholesterol-d7  Chemical Structure
  53. GC42595 7(Z),11(Z)-Heptacosadiene The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones. 7(Z),11(Z)-Heptacosadiene  Chemical Structure
  54. GC42596 7(Z),11(Z)-Nonacosadiene Le 7(Z),11(Z)-Nonacosadiène est la phéromone de Drosophila melanogaster À partir d'un dérivé de la tétrahydrophyridine. 7(Z),11(Z)-Nonacosadiene  Chemical Structure
  55. GC42597 7(Z),11(Z)-Pentacosadiene Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. 7(Z),11(Z)-Pentacosadiene  Chemical Structure
  56. GC42598 7(Z)-Pentacosene 7(Z)-Pentacosene is an unsaturated cuticular hydrocarbon that acts as a contact sex pheromone in fruit flies. 7(Z)-Pentacosene  Chemical Structure
  57. GC42599 7(Z)-Tricosene 7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila. 7(Z)-Tricosene  Chemical Structure
  58. GC46080 7,3',4'-Trihydroxyflavone 7,3',4'-La trihydroxyflavone est un composé aglycone flavonoÏde isolé des gousses de fèves. 7,3',4'-Trihydroxyflavone  Chemical Structure
  59. GC10533 7,8-dihydro-L-Biopterin La 7,8-dihydro-L-bioptérine est un produit d'oxydation de la tétrahydrobioptérine. 7,8-dihydro-L-Biopterin  Chemical Structure
  60. GC46735 7-Biopterin A pterin 7-Biopterin  Chemical Structure
  61. GC46736 7-Bromoheptanoic Acid A building block 7-Bromoheptanoic Acid  Chemical Structure
  62. GC46242 7-dehydro Cholesterol-d7

    7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol

    7-dehydro Cholesterol-d7  Chemical Structure
  63. GC13784 7-Ethoxyresorufin La 7-éthoxyrésorufine (éther éthylique de résorufine) est un substrat fluorométrique et un inhibiteur compétitif du cytochrome P450, en particulier du CYP1A1. 7-Ethoxyresorufin  Chemical Structure
  64. GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine 7-hydroxy Chlorpromazine (hydrochloride)  Chemical Structure
  65. GC42606 7-hydroxy Coumarin Glucuronide (sodium salt) 7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism. 7-hydroxy Coumarin Glucuronide (sodium salt)  Chemical Structure
  66. GC42607 7-hydroxy Coumarin sulfate (potassium salt) 7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS. 7-hydroxy Coumarin sulfate (potassium salt)  Chemical Structure
  67. GC49051 7-hydroxy Methotrexate Le 7-hydroxy méthotrexate est un métabolite majeur du méthotrexate 7-hydroxy Methotrexate  Chemical Structure
  68. GC42608 7-hydroxy Methotrexate (sodium salt)

    7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.

    7-hydroxy Methotrexate (sodium salt)  Chemical Structure
  69. GC10565 7-hydroxycoumarinyl Arachidonate L'arachidonate de 7-hydroxycoumarinyle (7-HCA) est un substrat fluorogène de la phospholipase cytosolique A2 (PLA2). 7-hydroxycoumarinyl Arachidonate  Chemical Structure
  70. GC42611 7-hydroxycoumarinyl-γ-Linolenate 7-hydroxycoumarinyl-γ-Linolénate est un substrat fluorogène de la phospholipase A2 cytosolique (cPLA2). 7-hydroxycoumarinyl-γ-Linolenate  Chemical Structure
  71. GC65409 7-Methylcoumarin La 7-méthylcoumarine, une coumarine, présente une forte activité hépatoprotectrice et un puissant effet antioxydant. 7-Methylcoumarin  Chemical Structure
  72. GC18284 7-Methyluric Acid 7-Methyluric acid is a methylated purine and uric acid derivative. 7-Methyluric Acid  Chemical Structure
  73. GC42620 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) L'acide 8-aminopyrène-1,3,6-trisulfonique (sel de sodium) est un colorant fluorescent anionique soluble dans l'eau. 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt)  Chemical Structure
  74. GC52126 8-chloro Caffeine 8-chloro Caffeine  Chemical Structure
  75. GC35201 8-Geranyloxypsoralen Le 8-géranyloxypsoralène est une furanocoumarine isolée du pamplemousse, agit comme un puissant inhibiteur du P450 3A4 (CYP3A4) avec une IC50 de 3,93 μM. 8-Geranyloxypsoralen  Chemical Structure
  76. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine 8-hydroxy Amoxapine  Chemical Structure
  77. GC42626 8-hydroxy Efavirenz 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz. 8-hydroxy Efavirenz  Chemical Structure
  78. GC18654 8-hydroxy Loxapine 8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2. 8-hydroxy Loxapine  Chemical Structure
  79. GC49544 8-hydroxy Mirtazapine A metabolite of mirtazapine 8-hydroxy Mirtazapine  Chemical Structure
  80. GN10330 8-Methoxypsoralen 8-Methoxypsoralen  Chemical Structure
  81. GC42633 9(E)-Erythromycin A oxime (9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin . 9(E)-Erythromycin A oxime  Chemical Structure
  82. GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)  Chemical Structure
  83. GC45366 9(Z)-Pentacosene   9(Z)-Pentacosene  Chemical Structure
  84. GC42641 9(Z)-Tricosene (9Z)-Tricosene is a pheromone released by insects, including D. 9(Z)-Tricosene  Chemical Structure
  85. GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene Prostaglandin E2  Chemical Structure
  86. GC40470 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2  Chemical Structure
  87. GC42649 9-Nitrooleate Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate, cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. 9-Nitrooleate  Chemical Structure
  88. GC42651 9-oxo-10(E),12(E)-Octadecadienoic Acid 9-oxo-10(E),12(E)-Octadecadienoic acid (9-oxoODA) is a natural agonist, abundant in tomatoes, that activates PPARα at 10-20 μM. 9-oxo-10(E),12(E)-Octadecadienoic Acid  Chemical Structure
  89. GC46761 9-Oxononanoic Acid An oxidized fatty acid 9-Oxononanoic Acid  Chemical Structure
  90. GC50419 A 33 A 33 est un inhibiteur de PDE4B actif et sélectif par voie orale avec une IC50 de 15 nM. A 33  Chemical Structure
  91. GC13262 A-771726 dihydroorotate dehydrogenase inhibitor A-771726  Chemical Structure
  92. GC46765 A6770 A6770 est un puissant inhibiteur de la sphingosine 1-phosphate (S1P) lyase (S1PL) actif par voie orale. A6770  Chemical Structure
  93. GC15614 A922500 A diacylglycerol acyltransferase 1 inhibitor A922500  Chemical Structure
  94. GC15921 A939572 A939572 est un inhibiteur puissant et biodisponible de la stéaroyl-CoA désaturase1 (SCD1) avec des valeurs IC50 <4 nM et 37 nM pour mSCD1 et hSCD1, respectivement. A939572  Chemical Structure
  95. GC31355 AA26-9 AA26-9 est un inhibiteur puissant et À large spectre de la sérine hydrolase. AA26-9  Chemical Structure
  96. GC16115 AACOCF3

    Inhibiteur de la cPLA2/hydrolyse d'anandamide/FAAH

    AACOCF3  Chemical Structure
  97. GC42667 Abacavir Carboxylate Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir. Abacavir Carboxylate  Chemical Structure
  98. GC46768 Abaloparatide (acetate) A synthetic derivative of PTHrP and an agonist of PTHR1 Abaloparatide (acetate)  Chemical Structure
  99. GC17645 Abiraterone A CYP17A1 inhibitor and an active metabolite of abiraterone acetate Abiraterone  Chemical Structure
  100. GC11108 Abiraterone acetate A CYP17A1 inhibitor Abiraterone acetate  Chemical Structure
  101. GC64010 Abiraterone decanoate Le décanoate d'abiratérone est un puissant promédicament de l'abiratérone. Le décanoate d'abiratérone fournit une libération contrÔlée d'abiratérone et une inhibition du CYP17 À longue durée d'action avec administration intramusculaire (IM). Abiraterone decanoate  Chemical Structure

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