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Metabolism

  1. Numéro de catégorie Nom du produit Informations
  2. GC66197 α-?Terpinyl acetate α-L'acétate de terpinyle est un ester monoterpénique isolé de l'huile essentielle de Laurus nobilis L.. α-L'acétate de terpinyle est un substrat P450 2B6 compétitif qui se lie au site actif de P450 2B6 avec une valeur Kd de 5,4μM. α-?Terpinyl acetate  Chemical Structure
  3. GC11123 α-CEHC A major metabolite of δ-tocopherol α-CEHC  Chemical Structure
  4. GC48276 α-Cyclodextrin (hydrate) A cyclic hexasaccharide α-Cyclodextrin (hydrate)  Chemical Structure
  5. GC48278 α-D-Glucose-1,6-bisphosphate (potassium salt hydrate) A bis-phosphorylated derivative of α-D-glucose α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)  Chemical Structure
  6. GC48279 α-D-Glucose-1-phosphate (sodium salt hydrate) An intermediate in glycogen metabolism α-D-Glucose-1-phosphate (sodium salt hydrate)  Chemical Structure
  7. GC52253 α-Enolase (1-19)-biotin Peptide A biotinylated α-enolase peptide α-Enolase (1-19)-biotin Peptide  Chemical Structure
  8. GC45208 α-hydroxy Metoprolol α-hydroxy Metoprolol is an active metabolite of the β1-adrenergic receptor blocker metoprolol. α-hydroxy Metoprolol  Chemical Structure
  9. GC45210 α-Linolenic Acid (sodium salt) α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. α-Linolenic Acid (sodium salt)  Chemical Structure
  10. GC48283 α-Linolenic Acid-d14 An internal standard for the quantification of αLinolenic acid α-Linolenic Acid-d14  Chemical Structure
  11. GC45602 α-Linolenic Acid-d5 MaxSpec• Standard   α-Linolenic Acid-d5 MaxSpec• Standard  Chemical Structure
  12. GC49008 α-Muricholic Acid-d4 An internal standard for the quantification of α-muricholic acid α-Muricholic Acid-d4  Chemical Structure
  13. GC40480 α-Phenyl-α-(2-pyridyl)acetonitrile α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion. α-Phenyl-α-(2-pyridyl)acetonitrile  Chemical Structure
  14. GC45232 β-D-Glucosamine Pentaacetate β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production. β-D-Glucosamine Pentaacetate  Chemical Structure
  15. GC49647 β-Hyodeoxycholic Acid (hydrate) A 3β epimer of hyodeoxycholic acid β-Hyodeoxycholic Acid (hydrate)  Chemical Structure
  16. GC49007 β-Muricholic Acid-d4 An internal standard for the quantification of β-muricholic acid β-Muricholic Acid-d4  Chemical Structure
  17. GC41502 β-Myrcene β-Myrcène (β-β-Myrcène), un composé volatil aromatique, supprime l'activité NF-κB induite par le TNFα. β-Myrcene  Chemical Structure
  18. GC40551 γ-CEHC The major tocopherol obtained from natural dietary sources is γ-tocopherol, whereas α-tocopherol is the form of Vitamin E typically obtained from synthetic supplements. γ-CEHC  Chemical Structure
  19. GC52400 γ-Glu-Ala (trifluoroacetate salt) A dipeptide γ-Glu-Ala (trifluoroacetate salt)  Chemical Structure
  20. GC52404 γ-Glu-Phe (trifluoroacetate salt) A dipeptide with metabolism-altering activity γ-Glu-Phe (trifluoroacetate salt)  Chemical Structure
  21. GC45239 δ4-Abiraterone δ4-Abiratérone est un métabolite majeur de l'abiratérone. δ4-Abiratérone est un inhibiteur du CYP17A1, de la 3b-hydroxystéroÏde déshydrogénase (3βHSD) et de la stéroÏde-5a-réductase (SRD5A) et également un antagoniste du récepteur des androgènes. δ4-Abiraterone  Chemical Structure
  22. GC15975 α-Estradiol Le α-estradiol est un œstrogène faible et un inhibiteur de la 5α-réductase qui est utilisé comme médicament topique dans le traitement de l'alopécie androgénique. α-Estradiol  Chemical Structure
  23. GC49009 ω-Muricholic Acid-d4 An internal standard for the quantification of ω-MCA ω-Muricholic Acid-d4  Chemical Structure
  24. GC49296 τ-Fluvalinate A pyrethroid acaricide τ-Fluvalinate  Chemical Structure
  25. GC46314 (±)-β-Hydroxybutyrate-d4 (sodium salt) An internal standard for the quantification of (±)βhydroxybutyrate (±)-β-Hydroxybutyrate-d4 (sodium salt)  Chemical Structure
  26. GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid  Chemical Structure
  27. GC52013 (±)-10-hydroxy-12(Z)-Octadecenoic Acid An oxylipin and metabolite of linoleic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid  Chemical Structure
  28. GC52421 (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5  Chemical Structure
  29. GC41661 (±)-4-hydroxy Propranolol β-D-Glucuronide (±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol. (±)-4-hydroxy Propranolol β-D-Glucuronide  Chemical Structure
  30. GC46284 (±)-Cotinine-d3 An internal standard for the quantification of cotinine (±)-Cotinine-d3  Chemical Structure
  31. GC41671 (±)-Equol 4'-sulfate (sodium salt)

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.

    (±)-Equol 4'-sulfate (sodium salt)  Chemical Structure
  32. GC41315 (±)-Ketoprofen Glucuronide (±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen. (±)-Ketoprofen Glucuronide  Chemical Structure
  33. GC40954 (±)-N-3-Benzylnirvanol (±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (-)-N-3-benzylnirvanol. (±)-N-3-Benzylnirvanol  Chemical Structure
  34. GC39271 (±)-Naringenin (±)-La naringénine est un flavonoïde naturel. (±)-Naringenin  Chemical Structure
  35. GC45618 (±)-trans-GK563 A GVIA iPLA2 inhibitor (±)-trans-GK563  Chemical Structure
  36. GC40802 (±)12(13)-DiHOME

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

    (±)12(13)-DiHOME  Chemical Structure
  37. GC40270 (±)5(6)-DiHET

    5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases.

    (±)5(6)-DiHET  Chemical Structure
  38. GC40282 (+)-5-trans Cloprostenol Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol  Chemical Structure
  39. GC45260 (+)-Cloprostenol isopropyl ester (+)-Ester isopropylique de cloprosténol, une prostaglandine F2α ; analogues, est l'intermédiaire du (+)-cloprosténol. (+)-Cloprostenol isopropyl ester  Chemical Structure
  40. GC45262 (+)-Cloprostenol methyl ester (+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). (+)-Cloprostenol methyl ester  Chemical Structure
  41. GC45264 (+)-Geodin (+) - La géodine, un métabolite fongique, présente une activité antibactérienne. (+)-Geodin  Chemical Structure
  42. GC12404 (+)-Ketoconazole (+)-Kétoconazole ((+)-R 41400) est un agent antifongique imidazole, un inhibiteur du CYP3A4. (+)-Ketoconazole  Chemical Structure
  43. GC30424 (-)-Cephaeline dihydrochloride (NSC 32944) Le (-)-dichlorhydrate de céphaéline (NSC 32944) est un inhibiteur sélectif du CYP2D6 avec une CI50 de 121 μM. (-)-Cephaeline dihydrochloride (NSC 32944)  Chemical Structure
  44. GC18343 (-)-CP 55,940 (-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively. (-)-CP 55,940  Chemical Structure
  45. GC45248 (-)-FINO2 Le (-)-FINO2 est un puissant inducteur de la ferroptose. (-)-FINO2 inhibe l'activité de GPX4. (-)-FINO2 est un oxydant stable qui oxyde le fer ferreux et stable À différents niveaux de pH. (-)-FINO2 provoque une peroxydation lipidique généralisée. (-)-FINO2  Chemical Structure
  46. GC14520 (-)-p-Bromotetramisole Oxalate L'oxalate de (-)-p-bromotétramisole est un inhibiteur puissant et non spécifique de la phosphatase alcaline. (-)-p-Bromotetramisole Oxalate  Chemical Structure
  47. GC45252 (-)-Sitagliptin Carbamoyl Glucuronide (-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. (-)-Sitagliptin Carbamoyl Glucuronide  Chemical Structure
  48. GC18622 (2'S)-Nicotine-1-oxide (2'S)-Nicotine-1-oxide is a metabolite of nicotine . (2'S)-Nicotine-1-oxide  Chemical Structure
  49. GC41691 (2R)-Glycerol-O-β-D-galactopyranoside (2R)-Glycérol-O-β-D-galactopyranoside (3-O-β-D-Galactopyranosyl-sn-glycérol) est un bon substrat pour les trois composants de l'opéron lac, i. (2R)-Glycerol-O-β-D-galactopyranoside  Chemical Structure
  50. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt)  Chemical Structure
  51. GC41694 (3S)-hydroxy Quinidine (3S)-hydroxy Quinidine is an active quinidine metabolite. (3S)-hydroxy Quinidine  Chemical Structure
  52. GC60396 (3S,5R)-Fluvastatin sodium La (3S,5R)-fluvastatine sodique ((3S,5R)-XU 62-320) est l'énantiomère (3S,5R) de la fluvastatine. (3S,5R)-Fluvastatin sodium  Chemical Structure
  53. GC68317 (3S,5R)-Fluvastatin-d6 sodium (3S,5R)-Fluvastatin-d6 sodium  Chemical Structure
  54. GC13751 (3S,5S)-Atorvastatin (sodium salt) negetive control of Atorvastatin, HMG-CoA reductase inhibitor (3S,5S)-Atorvastatin (sodium salt)  Chemical Structure
  55. GC46333 (4′-Hydroxy)phenoxybenzoic Acid A pyrethroid insecticide metabolite (4′-Hydroxy)phenoxybenzoic Acid  Chemical Structure
  56. GC48508 (4-Carboxybutyl-d4)triphenylphosphonium (bromide) An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium (4-Carboxybutyl-d4)triphenylphosphonium (bromide)  Chemical Structure
  57. GC41695 (6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride) (6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. (6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)  Chemical Structure
  58. GC41088 (6S)-Tetrahydrofolic Acid (6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid, a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism. (6S)-Tetrahydrofolic Acid  Chemical Structure
  59. GC34980 (E)-Ferulic acid L'acide (E)-férulique est un isomère de l'acide férulique qui est un composé aromatique, abondant dans les parois cellulaires des plantes. L'acide (E)-férulique provoque la phosphorylation de la β-caténine, entraÎnant une dégradation protéasomique de la β-caténine et augmente l'expression du facteur pro-apoptotique Bax et diminue l'expression du facteur pro-survie survivine. L'acide (E)-férulique montre une puissante capacité À éliminer les espèces réactives de l'oxygène (ROS) et inhibe la peroxydation des lipides. L'acide (E)-férulique exerce À la fois des effets anti-prolifération et anti-migration dans la lignée cellulaire H1299 du cancer du poumon humain. (E)-Ferulic acid  Chemical Structure
  60. GC40286 (E,Z)-2-propyl-2-Pentenoic Acid (E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. (E,Z)-2-propyl-2-Pentenoic Acid  Chemical Structure
  61. GC49189 (E/Z)-4-hydroxy Tamoxifen-d5 An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen (E/Z)-4-hydroxy Tamoxifen-d5  Chemical Structure
  62. GC34984 (R)-(-)-Rolipram Le (R)-(-)-Rolipram est l'énantiomère R du Rolipram. (R)-(-)-Rolipram  Chemical Structure
  63. GC25001 (R)-Avanafil R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM. (R)-Avanafil  Chemical Structure
  64. GC40678 (R)-Bromoenol lactone Le (R)-bromoénol lactone ((R)-BEL) est un inhibiteur irréversible, chiral, basé sur le mécanisme de la phospholipase γ indépendante du calcium (iPLA2γ). (R)-Bromoenol lactone  Chemical Structure
  65. GC52290 (R)-HTS-3 An inhibitor of LPCAT3 (R)-HTS-3  Chemical Structure
  66. GC67864 (R)-Irsenontrine (R)-Irsenontrine  Chemical Structure
  67. GC41722 (R,S)-Carvedilol Glucuronide (R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R,S)-Carvedilol Glucuronide  Chemical Structure
  68. GC61548 (Rac)-5-Keto Fluvastatin (Rac)-5-Keto Fluvastatin (3-Hydroxy-5-Keto Fluvastatin) est une impureté de Fluvastatin (XU 62320). (Rac)-5-Keto Fluvastatin  Chemical Structure
  69. GC62743 (Rac)-EC5026 (Rac)-EC5026 ((Rac)-BPN-19186) est un puissant inhibiteur pipéridine de l'époxyde hydrolase soluble (sEH) extrait du brevet WO2019156991A1, page 39, a un Ki de 0,06 nM. (Rac)-EC5026  Chemical Structure
  70. GC61750 (Rac)-Indoximod Le (Rac)-indoximod (1-méthyl-DL-tryptophane) est un inhibiteur de l'indoleamine 2,3-dioxygénase (IDO). (Rac)-Indoximod  Chemical Structure
  71. GC46347 (S)-(+)-Methoprene Le (S)-méthoprène est un analogue de l'hormone juvénile qui empêche l'insecte de passer de la pupe à l'adulte et est utilisé comme insecticide. (S)-(+)-Methoprene  Chemical Structure
  72. GC40679 (S)-Bromoenol lactone Le (S)-bromoénol lactone ((S)-BEL) est un inhibiteur irréversible, chiral, basé sur le mécanisme de la phospholipase A2β indépendante du calcium (iPLA2β) qui inhibe la libération d'arachidonate induite par la vasopressine À partir de culture de muscle lisse aortique de rat (A10) cellules avec une IC50 de 2 μM. (S)-Bromoenol lactone  Chemical Structure
  73. GC50321 (S)-C33 Le (S)-C33 est un inhibiteur puissant et sélectif de la PDE9 (phosphodiestérase-9), avec une IC50 de 11 nM. (S)-C33  Chemical Structure
  74. GC48719 (S)-Canadine La (S)-Canadine est un alcaloÏde et un intermédiaire dans la biosynthèse de la berbérine avec une activité insecticide. (S)-Canadine  Chemical Structure
  75. GC46352 (S)-DO271 An inactive control for DO264 (S)-DO271  Chemical Structure
  76. GC49520 (S)-Equol Le (S)-Equol est un ligand de haute affinité pour le récepteur β des œstrogènes avec un Ki de 0,73 nM. (S)-Equol  Chemical Structure
  77. GC60417 (S)-Indoximod Le (S)-indoximod (1-méthyl-L-tryptophane) est un inhibiteur de l'indoleamine 2,3-dioxygénase (IDO). Le (S)-indoximod peut être utilisé pour la recherche sur le cancer. (S)-Indoximod  Chemical Structure
  78. GC40145 (S)-Laudanosine (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine  Chemical Structure
  79. GC14486 (S)-Mephenytoin La (S)-méphénytoÏne ((+)-méphénytoÏne) est un agent anticonvulsivant. (S)-Mephenytoin  Chemical Structure
  80. GC49179 (S)-O-Desmethyl Naproxen A metabolite of (S)-naproxen (S)-O-Desmethyl Naproxen  Chemical Structure
  81. GC18596 (±)-2-propyl-4-Pentenoic Acid L'acide (±)-2-propyl-4-penténoÏque (4-en-VPA) est un métabolite toxique majeur de l'acide valproÏque. (±)-2-propyl-4-Pentenoic Acid  Chemical Structure
  82. GC49034 1(R)-(Trifluoromethyl)oleyl alcohol An oleic acid analog 1(R)-(Trifluoromethyl)oleyl alcohol  Chemical Structure
  83. GC46365 1,1'-(Azodicarbonyl)dipiperidine A Mitsunobu reagent 1,1'-(Azodicarbonyl)dipiperidine  Chemical Structure
  84. GC41762 1,2,3,5-Tetra-O-acetyl-D-xylofuranose Le 1,2,3,5-tétra-O-acétyl-D-xylofuranose est la matière première pour la synthèse des nucléotides. 1,2,3,5-Tetra-O-acetyl-D-xylofuranose  Chemical Structure
  85. GC46040 1,2,3-Trielaidoyl-rac-glycerol A triacylglycerol 1,2,3-Trielaidoyl-rac-glycerol  Chemical Structure
  86. GC45698 1,2,3-Triheptanoyl-rac-glycerol Le 1,2,3-triheptanoyl-rac-glycérol (propane-1,2,3-triyl triheptanoate) est un triglycéride synthétique À chaÎne moyenne (MCT) composé de trois acides gras À chaÎne impaire À 7 carbones (heptanoate) sur un glycérol colonne vertébrale. 1,2,3-Triheptanoyl-rac-glycerol  Chemical Structure
  87. GC45285 1,2,3-Trihexanoyl-rac-glycerol   1,2,3-Trihexanoyl-rac-glycerol  Chemical Structure
  88. GC45956 1,2,3-Trinonanoyl-rac-glycerol A triacylglycerol 1,2,3-Trinonanoyl-rac-glycerol  Chemical Structure
  89. GC46009 1,2,3-Trioctanoyl-rac-glycerol-13C3 An internal standard for the quantification of 1,2,3-trioctanoyl glycerol-13C3 1,2,3-Trioctanoyl-rac-glycerol-13C3  Chemical Structure
  90. GC46373 1,2,3-Triundecanoyl Glycerol A triacylglycerol 1,2,3-Triundecanoyl Glycerol  Chemical Structure
  91. GC41782 1,2-bis(heptanoylthio) Glycerophosphocholine Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). 1,2-bis(heptanoylthio) Glycerophosphocholine  Chemical Structure
  92. GC40236 1,2-Dilinoleoyl-sn-glycerol 1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. 1,2-Dilinoleoyl-sn-glycerol  Chemical Structure
  93. GC41808 1,2-Dioctanoyl PC

    Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane.

    1,2-Dioctanoyl PC  Chemical Structure
  94. GC41837 1,3,7-Trimethyluric Acid L'acide 1,3,7-triméthylurique est le métabolite de la caféine. Le rapport métabolique de l'acide 1,3,7-triméthylurique À la caféine peut être évalué en tant que biomarqueur pour décrire la variabilité de l'activité du CYP3A dans une cohorte. 1,3,7-Trimethyluric Acid  Chemical Structure
  95. GC46387 1,3,7-Trimethyluric Acid-d9 An internal standard for the quantification of 1,3,7-trimethyluric acid 1,3,7-Trimethyluric Acid-d9  Chemical Structure
  96. GC41846 1,3-Dioctanoyl-2-Oleoyl-rac-glycerol 1,3-Dioctanoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. 1,3-Dioctanoyl-2-Oleoyl-rac-glycerol  Chemical Structure
  97. GC41849 1,3-Dipalmitoleoyl-rac-glycerol 1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. 1,3-Dipalmitoleoyl-rac-glycerol  Chemical Structure
  98. GC40167 1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-docosahexaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. 1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol  Chemical Structure
  99. GC41850 1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position. 1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol  Chemical Structure
  100. GC19528 1,4-Benzoquinone A toxic metabolite of benzene 1,4-Benzoquinone  Chemical Structure
  101. GC41858 1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)

    1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis.

    1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)  Chemical Structure

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