Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. Nom du produit Informations
- GC46387 1,3,7-Trimethyluric Acid-d9 An internal standard for the quantification of 1,3,7-trimethyluric acid
- GC41846 1,3-Dioctanoyl-2-Oleoyl-rac-glycerol 1,3-Dioctanoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.
- GC41849 1,3-Dipalmitoleoyl-rac-glycerol 1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions.
- GC40167 1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-docosahexaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position.
- GC41850 1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position.
- GC19528 1,4-Benzoquinone A toxic metabolite of benzene
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GC41858
1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis.
- GC40741 1,6-Anhydro-D-galactose 1,6-Anhydro-D-galactose is a carbohydrate found in liquid smoke flavorings that is used as a tracer of the contribution of biomass burning to total atmospheric particulate matter.
- GC40328 1,7-Dimethyluric Acid L'acide 1,7-diméthylurique est le métabolite de la caféine.
- GC42051 1-β-D-Glucosylsphingosine (d18:1) 1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.
- GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine
- GC46477 1-Amino-1-deoxy-D-fructose (hydrochloride) An amino monosaccharide
- GC39221 1-Cyclohexyl-3-dodecyl urea La 1-Cyclohexyl-3-dodécyl urée (CDU; N-Cyclohexyl-N-dodécyl urée; NCND) est un inhibiteur hautement sélectif de l'époxyde hydrolase soluble (sEH).
- GC17913 1-Deazaadenosine La 1-déazaadénosine est un puissant inhibiteur de l'adénosine désaminase (ADA) avec une valeur Ki de 0,66 μM. La 1-déazaadénosine présente des activités anticancéreuses in vitro et a le potentiel d'être un agent chimiothérapeutique pour les troubles lymphoprolifératifs.
- GC10430 1-Deoxygalactonojirimycin (hydrochloride) La 1-désoxygalactonojirimycine (chlorhydrate) (GR181413A) est un inhibiteur puissant et compétitif de la α-galactosidase A (α-Gal A) avec une IC50 de 0,04 μM pour la &888-8889 humaine;
- GC18609 1-Deoxysphinganine (m18:0) La 1-désoxysphinganine (m18:0) (ES-285) est un composé antiprolifératif (antitumoral) d'origine marine. La 1-désoxysphinganine (m18:0) inhibe la croissance des cellules prostatiques PC-3 et LNCaP par accumulation intracellulaire de céramide et PKC&zeta ; Activation.
- GC33073 1-Ethynylnaphthalene Le 1-éthynylnaphtalène est un inhibiteur sélectif du cytochrome P450 1B1.
- GC35065 1-Linoleoyl Glycerol Le 1-linoléoyl glycérol est un glycérol d'acide gras.
- GC35068 1-Monomyristin La 1-monomyristine, extraite de Serenoa repens, inhibe l'hydrolyse du 2-oléoylglycérol (IC50=32 μM) et l'activité de l'amide hydrolase d'acide gras (FAAH) (IC50=18 μM).
- GC33457 1-Naphthaleneacetic acid (1-Naphthylacetic acid) Acide 1-naphtalèneacétique (acide 1-naphtylacétique) (acide 1-naphtylacétique), une auxine synthétique, peut favoriser la croissance des plantes.
- GC13379 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC42029 1-Palmitoyl-2-linoleoyl PE Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis.
- GC49366 1-Salicylate Glucuronide A metabolite of salicylic acid and aspirin
- GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE
- GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42049 1-thio-β-D-Glucose (sodium salt) 1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position.
- GC48782 10,13-epoxy-11-methyl-Octadecadienoic Acid A furan fatty acid
- GC49872 10-Formyltetrahydrofolate (sodium salt) (technical grade) Le 10-formyltétrahydrofolate (sel de sodium) (qualité technique) est une forme d'acide tétrahydrofolique qui agit comme donneur de groupes formyle dans l'anabolisme.
- GC49118 10-hydroxy Warfarin A metabolite of (R)-warfarin
- GC41867 10-Nitrolinoleate Le 10-nitrolinoléate est un puissant récepteur activé par les proliférateurs de peroxysomes γ ; (PPARγ) agoniste.
- GC41868 10-Nitrooleate Le 10-nitrooléate (CXA-10), un acide gras nitré, a des effets potentiels dans les états pathologiques dans lesquels le stress oxydatif, l'inflammation, la fibrose et/ou la toxicité tissulaire directe jouent un rÔle important.
- GC52026 10-oxo-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite
- GC52071 10-oxo-12(Z)-Octadecenoic Acid A metabolite of linoleic acid and an activator of TRPV1
- GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
- GC40319 10-PAHSA 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC11055 10-Pyrene-PC A substrate for some PLA2s
- GC41410 11β-Prostaglandin E2 11β-Prostaglandine E2 (11β-Dinoprostone), un dérivé de prostanoÏde, inhibe la liaison de [3H]PGE2 aux membranes hypothalamiques chez le rat avec un Ki de 53,3 nM.
- GC10821 11-keto-β-Boswellic Acid L'acide 11-céto-bêta-boswellique (11-céto-β -acide boswellique) est un acide triterpénique pentacyclique de la résine d'oléogume de l'écorce de l'arbre dentelé Boswellia, populairement connu sous le nom d'encens indien. L'acide 11-céto-bêta-boswellique a une activité anti-inflammatoire principalement due À l'inhibition de la 5-lipoxygénase (5-LOX) et de l'activation ultérieure des leucotriènes et du facteur nucléaire kappa B (NF-κ B) et de la génération alpha du facteur de nécrose tumorale production.
- GC63796 116-9e 116-9e (MAL2-11B) est un inhibiteur de l'ADNJA1 co-chaperon Hsp70.
- GC64008 12-O-Methylcarnosic acid L'acide 12-O-méthylcarnosique (acide 12-méthoxycarnosique), un acide carnosique diterpène isolé de l'extrait acétonique de Salvia microphylla, est un constituant actif de l'inhibition de la 5α-réductase avec une valeur IC50 de 61,7 μM.
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GC41434
13,14-dihydro Prostaglandin F2α
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.
- GC41436 13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.
- GC46435 13-cis-Retinoic Acid-d5 An internal standard for the quantification of 13-cis retinoic acid
- GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
- GC41917 14-methyl Palmitic Acid 14-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, Aegean jellyfish (A.
- GC41166 15(S)-15-methyl Prostaglandin D2 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
- GC41167 15(S)-15-methyl Prostaglandin E2 15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2.
- GC41924 15(S)-15-methyl Prostaglandin F2α isopropyl ester 15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.
- GC18372 15(S)-15-methyl Prostaglandin F2α methyl ester 15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.
- GC13960 15-deoxy-Δ-12,14-Prostaglandin J2 La 15-désoxy-Δ-12,14-Prostaglandine J2 (15d-PGJ2) est une prostaglandine cyclopenténone et un métabolite de la PGD2.
- GC46447 15-deoxy-δ12,14-Prostaglandin J2-d4 An internal standard for the quantification of 15deoxyΔ12,14prostaglandin J2
- GC40582 15-keto Prostaglandin F1α 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH.
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GC41418
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α.
- GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
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GC41939
15-methyl Palmitic Acid
15-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, one-humped camel (C.
- GC18774 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α.
- GC49848 16-Ketoestradiol An active metabolite of estrone
- GC41946 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy PGF2α is a metabolically stable analog of PGF2α.
- GC40961 16-phenoxy tetranor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC41321 17α,20β-Dihydroxy-4-pregnen-3-one An endogenous, maturation-inducing steroid
- GC46470 17β-Estradiol-d2 1&7#946;-Estradiol-d2 (β-1&7#946;-Estradiol-d2) est l'estradiol marqué au deutérium.
- GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane.
- GC41955 17-DMAG 17-DMAG (17-DMAG) est un puissant inhibiteur de Hsp90, se liant À Hsp90 avec une CE50 de 62 ± ; 29 nM.
- GC13044 17-DMAG (Alvespimycin) HCl Le 17-DMAG (alvespimycine) HCl (chlorhydrate de 17-DMAG ; KOS-1022 ; BMS 826476) est un puissant inhibiteur de Hsp90, se liant À Hsp90 avec une EC50 de 62± ; 29 nM.
- GC48819 17-Epiestriol A metabolite of estrone
- GC41966 17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively).
- GC40392 17-phenyl trinor Prostaglandin F2α methyl ester 17-phényl trinor Prostaglandine F2α l'ester méthylique est une prodrogue du bimatoprost.
- GC41976 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC18816 19(R)-hydroxy Prostaglandin E1 19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man.
- GC49514 2′-Deoxyuridine-d2 An internal standard for the quantification of 2’-deoxyuridine
- GC52122 2’-Deoxyadenosine-5’-diphosphate (sodium salt) A nucleotide diphosphate
- GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
- GC46540 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate) A purine nucleotide
- GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
- GC46509 2,3,4,5-Tetrachlorophenol A metabolite of γ-lindane
- GC42058 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose is a D-glucopyranose derivative that has been used in glucosylation reactions.
- GC13836 2,3-dihydrothieno-Thiadiazole Carboxylate CYP450 enzymes (CYP2E1 and CYP2B4) inhibitor
- GC48459 2,3-Indolobetulin A derivative of betulin
- GC48444 2,3-Indolobetulonic Acid An inhibitor of α-glucosidase
- GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols
- GC41470 2,5-Anhydro-D-mannitol 2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver..
- GC49159 2-(1-Piperazinyl)pyrimidine An α2-AR antagonist and active metabolite of azapirones
- GC49330 2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride) A metabolite of mazindol
- GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide Le sulfure de 2-(E-2-décénoylamino)éthyl 2-(cyclohexyléthyl) est un composé qui inhibe l'ulcère induit par le stress et une faible toxicité, et peut maintenir la teneur en phospholipase A2 et en prostaglandine E2 chez les rats ulcérés induits par un stress restreint immergé dans l'eau.
- GC65414 2-(Tetradecylthio)acetic acid L'acide 2-tétradécylthio acétique est un activateur du récepteur activé par les proliférateurs de pan-peroxysomes (pan-PPAR).
- GC13956 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide Le sulfure de 2-acétamidophényl 5-chloro-2-nitrophényl (composé 2) est un puissant inhibiteur de la PDE7 (phosphodiestérase 7) avec une valeur IC50 de 2,1 μM.
- GC34186 2-Aminobenzenesulfonamide (Orthanilamide) Le 2-aminobenzènesulfonamide (orthanilamide) est un inhibiteur de l'anhydrase carbonique IX.
- GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase
- GC49272 2-Chloro-4-nitrophenyl α-D-maltotrioside A colorimetric α-amylase substrate
- GC42137 2-Chloro-4-nitrophenyl-α-D-glucopyranoside Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate.
- GC46539 2-Chloroadenine A heterocyclic building block
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GC41528
2-deoxy-2-fluoro L-Fucose
Le fucose est une désoxyhexose présente dans de nombreux organismes.
- GC48943 2-deoxy-2-fluoro-D-Glucose A glucose derivative with anticancer activity
- GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
- GC49223 2-deoxy-D-Glucose-13C6 An internal standard for the quantification of 2-deoxy-D-glucose
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GC19427
2-deoxy-D-Glucose-6-phosphate (sodium salt)
A synthetic analog of glucose used in cell metabolism and cancer research