PI3K/Akt/mTOR Signaling
Research Areas
Products Related to PI3K/Akt/mTOR Signaling(719)
- GC74025PIKfyve-IN-3Purity: >99.00%
PIKfyve-IN-3 (compound L22) has a remarkable interaction with PIKfyve kinase with a Kd value of 0.47 nM.
- GC74026DNA-PK-IN-12CAS: 2792146-91-7Purity: >99.00%
DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM.
- GC74029ASCT2-IN-1CAS: 3032651-18-3Purity: >98.00%
ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively.
- GC74030ASCT2-IN-2Purity: >99.00%
ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM.
- GC74261(R)-(+)-O-DemethylbuchenavianineCAS: 1364123-68-1Purity: >98.00%
(R)-(+)-O-Demetlbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK).
- GC78965ACT001 hydrochlorideCAS: 1403357-80-1Purity: >98.00%
ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent.
- GC79003WCY-8-67 TFAPurity: >99.00%
WCY-8-67 TFA is an orally active and selective USP5 inhibitor, with an IC 50 value of 1.33 μM.
- GC79104(Rac)-Chem-0199CAS: 122981-77-5Purity: >99.50%
(Rac)-Chem-0199 is the racemic mixture of Chem-0199.
- GC79141T7 Peptide TFAPurity: >98.00%
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.
- GC79175AMPK activator 19CAS: 1273323-44-6Purity: >98%
AMPK activator 19 (Compound 57), alkene oxindole derivative, is an AMPK activator.
- GC79176ARUK2010489Purity: >96.50%
ARUK2010489 (Compound 23) is a potent, selective and brain-penetrant NUAK1 inhibitor with a pIC 50 of 8.7.
- GC79177AMPK activator 18CAS: 1364692-88-5Purity: >98.00%
AMPK activator 18 is a potent allosteric activator of AMPK complexes containing the β2 isoform.
- GC79228Peptide R54 acetatePurity: >99.50%
Peptide R54 acetate (Pep R54 acetate) is a CXCR4 antagonist.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73992 | KTC1101 | 2764833-47-6 | >98.00% | |
KTC1101 is an orally active pan-PI3K inhibitor. | ||||
| GC74012 | MTX-531 | 2791417-66-6 | >99.00% | |
MTX-531 is an oral drug that inhibits EGFR (with an IC50 of 14.7 nM) and PI3K (with IC50 values of 6.4, 233, 8.3, and 1.1 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ respectively), and it has anti-tumor effects. | ||||
| GC74025 | PIKfyve-IN-3 | - | >99.00% | |
PIKfyve-IN-3 (compound L22) has a remarkable interaction with PIKfyve kinase with a Kd value of 0.47 nM. | ||||
| GC74026 | DNA-PK-IN-12 | 2792146-91-7 | >99.00% | |
DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. | ||||
| GC74029 | ASCT2-IN-1 | 3032651-18-3 | >98.00% | |
ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively. | ||||
| GC74030 | ASCT2-IN-2 | - | >99.00% | |
ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM. | ||||
| GC74044 | ARM165 | - | >99.00% | |
ARM165 is a heterobifunctional molecule. | ||||
| GC74094 | Leniolisib-d5 | - | >98.00% | |
Leniolisib-d5 is a deuterated labeled Leniolisib. | ||||
| GC74261 | (R)-(+)-O-Demethylbuchenavianine | 1364123-68-1 | >98.00% | |
(R)-(+)-O-Demetlbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). | ||||
| GC74689 | WRX606 | 899937-47-4 | >95.00% | |
WRX606 is an inhibitor for mTOR complex 1 (mTORC1). | ||||
| GC78798 | NN3201 | - | >99.00% | |
NN3201 is a c-Kit -targeting antibody-drug conjugate ( ADC ) with high affinity ( K D = 0.19 pM). | ||||
| GC78965 | ACT001 hydrochloride | 1403357-80-1 | >98.00% | |
ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent. | ||||
| GC78981 | HBS-101 | - | >99.50% | |
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor ( K D = 38.4 nM). | ||||
| GC79003 | WCY-8-67 TFA | - | >99.00% | |
WCY-8-67 TFA is an orally active and selective USP5 inhibitor, with an IC 50 value of 1.33 μM. | ||||
| GC79077 | DDO-6600 | 2640292-37-9 | >98.00% | |
DDO-6600 is a covalent Hsp90 inhibitor. | ||||
| GC79104 | (Rac)-Chem-0199 | 122981-77-5 | >99.50% | |
(Rac)-Chem-0199 is the racemic mixture of Chem-0199. | ||||
| GC79108 | AP4-43 | - | >99.50% | |
AP4-43 is an orally active CLK1, CLK4, PI3K, DDR1, EGFR and NEK4 inhibitor. | ||||
| GC79111 | CK2-TN03 | 313226-24-3 | >98.00% | |
CK2-TN03 is an ATP-competitive casein kinase 2 ( CK2 ) inhibitor, with an IC 50 of 165 nM and a K i of 20 nM. | ||||
| GC79117 | 8012–3246 | 421586-94-9 | >99.50% | |
8012-3246 is a selective PLK2 inhibitor with an IC 50 of 774.5 nM. | ||||
| GC79141 | T7 Peptide TFA | - | >98.00% | |
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor. | ||||
| GC79175 | AMPK activator 19 | 1273323-44-6 | >98% | |
AMPK activator 19 (Compound 57), alkene oxindole derivative, is an AMPK activator. | ||||
| GC79176 | ARUK2010489 | - | >96.50% | |
ARUK2010489 (Compound 23) is a potent, selective and brain-penetrant NUAK1 inhibitor with a pIC 50 of 8.7. | ||||
| GC79177 | AMPK activator 18 | 1364692-88-5 | >98.00% | |
AMPK activator 18 is a potent allosteric activator of AMPK complexes containing the β2 isoform. | ||||
| GC79228 | Peptide R54 acetate | - | >99.50% | |
Peptide R54 acetate (Pep R54 acetate) is a CXCR4 antagonist. | ||||