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Home >> Signaling Pathways >> PI3K/Akt/mTOR Signaling >> PI4K

PI4K

PI4K (phosphatidylinositol 4-kinase) catalyzes the first committed steps for phosphatidylinositol 4,5-bisphosphate biosynthesis. It is associated with viral replication and cancer.

Products for  PI4K

  1. Cat.No. Product Name Information
  2. GC32381 BF738735 BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM. BF738735 Chemical Structure
  3. GC32163 BQR-695 (NVP-BQR695)

    NVP-BQR695

     BQR-695 (NVP-BQR695) is a PI4KIIIβ inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively. BQR-695 (NVP-BQR695) Chemical Structure
  4. GC65309 GSK-F1 GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 Chemical Structure
  5. GC32118 KDU691 An antimalarial compound KDU691 Chemical Structure
  6. GC38033 KDU731 KDU731, an orally active C. KDU731 Chemical Structure
  7. GC62109 MMV390048 MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 ?M). MMV390048 Chemical Structure
  8. GC39155 PI-273 PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis. PI-273 Chemical Structure
  9. GC72785 PI4K-IN-1 PI4K-IN-1 (compound 44) is a potent PI4KIII inhibitor, with pIC50 values of 9.0 and 6.6 for PI4KIIIα and PI4KIIIβ, respectively. PI4K-IN-1 Chemical Structure
  10. GC15508 PI4KIII beta inhibitor 3

    PI4KIII beta inhibitor 3

     PI4KIII beta inhibitor 3 Chemical Structure
  11. GC30777 PI4KIIIbeta-IN-10 PI4KIIIbeta-IN-10 is a potent PI4KIIIβ inhibitor with an IC50 of 3.6 nM. PI4KIIIbeta-IN-10 Chemical Structure
  12. GC32847 PI4KIIIbeta-IN-9 PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively. PI4KIIIbeta-IN-9 Chemical Structure
  13. GC13089 PIK-93 PI3Kγ/PI4KIIIβ/PI3Kα inhibitor PIK-93 Chemical Structure
  14. GC32199 T-00127_HEV1 T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM. T-00127_HEV1 Chemical Structure
  15. GC18164 UCB9608

    PI4KIIIβ inhibitor

     UCB9608 Chemical Structure

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