Sorafenib (D3) (Synonyms: BAY 43-9006-d3) |
| Catalog No.GC37664 |
An internal standard for the quantification of sorafenib
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1130115-44-4
Sample solution is provided at 25 µL, 10mM.
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Sorafenib D3 (Bay 43-9006 D3) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
[1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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