MAPK Signaling
Research Areas
Products Related to MAPK Signaling(660)
- GC71682SalbutamolCAS: 18559-94-9Purity: >98.00%
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity.
- GC72094PKA RII peptide TFAPurity: >99.50%
PKA RII peptide TFA is a PKA substrate that, after being phosphorylated at the serine residue, can be used for the detection of calcineurin activity.
- GC72100MK2-IN-5 acetate
MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (Ki= 8 μM).
- GC72124CREBtide TFAPurity: >98.00%
CREBtide TFA is a CREB (cAMP response element binding protein)-like peptide.
- GC72756(E/Z)-NecrosulfonamideCAS: 432531-71-0Purity: >98.00%
(E/Z)-Necrosulfonamide is a racemic compound of Necrosulfonamide.
- GC73012HPK1-IN-2 dihydrochlorideCAS: 2375595-72-3Purity: >98.00%
HPK1-IN-2 didrochloride is a potent and orally active hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50<0.05 µΜ) with antitumor activity.
- GC730853-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazolesCAS: 287196-91-2Purity: >99.00%
3-droxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is an inhibitor for bone morphogenetic protein 2 (BMP2) with an IC50 of 2.2 μM.
- GC73214(3S,4R)-GNE-6893CAS: 2415374-97-7Purity: >99.00%
(3S,4R)-GNE-6893 is a potent and orally active HPK1 inhibitor.
- GC73312(R)-STU104CAS: 2767124-77-4Purity: >99.00%
(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation.
- GC73424PRT062607 acetateCAS: 1370261-98-5Purity: >99.00%
PRT062607 (P505-15) acetate is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis.
- GC73433(S)-BAY 2965501CAS: 2732902-09-7Purity: >99.00%
(S)-BAY 2965501 is the left-handed isomer of BAY 2965501.
- GC73438HPK1-IN-34CAS: 2380300-99-0Purity: >95.00%
HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <100 nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC71682 | Salbutamol | 18559-94-9 | >98.00% | |
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. | ||||
| GC72094 | PKA RII peptide TFA | - | >99.50% | |
PKA RII peptide TFA is a PKA substrate that, after being phosphorylated at the serine residue, can be used for the detection of calcineurin activity. | ||||
| GC72100 | MK2-IN-5 acetate | - | - | |
MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (Ki= 8 μM). | ||||
| GC72124 | CREBtide TFA | - | >98.00% | |
CREBtide TFA is a CREB (cAMP response element binding protein)-like peptide. | ||||
| GC72756 | (E/Z)-Necrosulfonamide | 432531-71-0 | >98.00% | |
(E/Z)-Necrosulfonamide is a racemic compound of Necrosulfonamide. | ||||
| GC72868 | AZA197 | 1249398-09-1 | >98.00% | |
AZA197 is a selective small molecule inhibitor of Cdc42. | ||||
| GC72910 | DD1 | 187585-11-1 | >99.00% | |
DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. | ||||
| GC73012 | HPK1-IN-2 dihydrochloride | 2375595-72-3 | >98.00% | |
HPK1-IN-2 didrochloride is a potent and orally active hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50<0.05 µΜ) with antitumor activity. | ||||
| GC73030 | RSK4-IN-1 TFA | - | - | |
RSK4-IN-1 TFA is a potent RSK4 inhibitor with a IC50 value of 9.5 nM. | ||||
| GC73082 | (R)-VX-11e | 1680187-43-2 | >98.00% | |
(R)-VX-11e (Compound 1) is an ERK2 inhibitor. | ||||
| GC73085 | 3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles | 287196-91-2 | >99.00% | |
3-droxy-4-carboxyalkylamidino-5-arylamino-isothiazoles is an inhibitor for bone morphogenetic protein 2 (BMP2) with an IC50 of 2.2 μM. | ||||
| GC73118 | EB1 | 42951-68-8 | >99.00% | |
EB1 is the inhibitor of kinases MNK with IC50s of 0.69 μM (MNK1) and 9.4 μM (MNK2). | ||||
| GC73145 | I-287 | 2014368-93-3 | >99.00% | |
I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. | ||||
| GC73213 | GNE-6893 | 2415374-98-8 | >99.00% | |
GNE-6893 is a potent and orally active HPK1 inhibitor. | ||||
| GC73214 | (3S,4R)-GNE-6893 | 2415374-97-7 | >99.00% | |
(3S,4R)-GNE-6893 is a potent and orally active HPK1 inhibitor. | ||||
| GC73234 | MY-673 | 2944459-96-3 | >98.00% | |
MY-673 is a colchicine binding site inhibitor (CBSI), that inhibits tubulin polymerization. | ||||
| GC73312 | (R)-STU104 | 2767124-77-4 | >99.00% | |
(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC50s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. | ||||
| GC73340 | SHR2415 | 2494010-42-1 | >98.00% | |
SHR2415 is a highly potent, selective and orally active ERK1/2 inhibitor. | ||||
| GC73424 | PRT062607 acetate | 1370261-98-5 | >99.00% | |
PRT062607 (P505-15) acetate is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis. | ||||
| GC73432 | CFT1946 | 2882165-79-7 | >99.00% | |
CFT1946 is an orally active, CRBN-based and mutant-selective bifunctional degradation activating compound (BiDAC™) degrader of BRAFV600E with a DC50 of 14 nM in A375 cells. | ||||
| GC73433 | (S)-BAY 2965501 | 2732902-09-7 | >99.00% | |
(S)-BAY 2965501 is the left-handed isomer of BAY 2965501. | ||||
| GC73438 | HPK1-IN-34 | 2380300-99-0 | >95.00% | |
HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <100 nM. | ||||
| GC73446 | MEK-IN-6 | 2845151-86-0 | >98.00% | |
MEK-IN-6 (Example 69) is a MEK inhibitor. | ||||
| GC73459 | B-Raf IN 15 | 832107-31-0 | >98.00% | |
B-Raf IN 15 (Compound 7) is a BRAF inhibitor. | ||||