GLPBio

Microbiology & Virology

Read More about this category
Microbiology & Virology

Microbiology & Virology

A virus is a small infectious agent that replicates inside living cells. Viruses cause many human diseases from small illnesses, like influenza, to more deadly diseases, like hepatitis B and HIV. Our body’s immune system defends against viral infection by generating specific antibodies to bind to and neutralize viral particles and by cell mediated immunity that destroys infected host cells.

Research Areas

Products Related to Microbiology & Virology(3940)

  • GC71131 structure
    GC71131Ristocetin
    CAS: 1404-55-3
    Purity: >98.00%

    Ristocetin is a glycopeptide antibiotic.

  • GC71138 structure
    GC71138NDM-1 inhibitor-3
    Purity: >99.00%

    NDM-1 inhibitor-3 (Compound 89) is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor with a Ki of 4 μM.

  • GC71142 structure
    GC71142ATP synthase inhibitor 2
    CAS: 2814540-76-4
    Purity: >99.00%

    ATP synthase inhibitor 2 is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL).

  • GC71194 structure
    GC71194LY1
    CAS: 2883813-32-7
    Purity: >98.00%

    LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PLpro and Mpro with Kd values of 1.5 μM and 2.3 μM for Mpro C145A protein and PLpro C111A protein, respectively.

  • GC71202 structure
    GC71202Antibacterial agent 131
    Purity: >98.00%

    Antibacterial agent 131 is a quinoline derivative.

  • GC71221 structure
    GC71221Leritrelvir
    CAS: 2923310-64-7

    Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a Ki of 8.6 nM.

  • GC71227 structure
    GC71227PYR01
    CAS: 2560576-15-8
    Purity: >98.00%

    PYR01 is a potent HIV-1 nonnucleoside reverse transcriptase inhibitor.

  • GC71228 structure
    GC71228Pomotrelvir
    CAS: 2713437-86-4
    Purity: >95.00%

    Pomotrelvir (PBI-0451) is a selective, orally active SARS-CoV-2 3CL protease inhibitor.

  • GC71234 structure
    GC71234IpOHA
    CAS: 132418-03-2
    Purity: >98.00%

    IpOHA is a potent plant KARI inhibitor.

  • GC71238 structure
    GC71238Antifungal agent 48
    CAS: 2142003-75-4

    Antifungal agent 48 (Example 308) is an antifungal agent.

  • GC71239 structure
    GC71239Antifungal agent 49
    CAS: 1414861-21-4

    Antifungal agent 49 (Example 112) is an antifungal agent.

  • GC71244 structure
    GC71244UC-781
    CAS: 178870-32-1

    UC-781 (NSC 675186) is a highly potent and selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an IC50 value of 5 nM.

  • GC71247 structure
    GC71247GRL-1720 TFA
    Purity: >94.00%

    GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 value of 15 μM.

  • GC71253 structure
    GC71253ARC7
    CAS: 681212-58-8
    Purity: >99.00%

    ARC7 can act as a probe for secondary metabolism in S. coelicolor.

  • GC71264 structure
    GC71264Mosnodenvir
    CAS: 2043343-94-6
    Purity: >99.00%

    Mosnodenvir (JNJ-1802) is a pan-serotype dengue antiviral agent with a high barrier to resistance, and is safe and well-tolerated.

  • GC71273 structure
    GC71273C12-TLRa
    Purity: >99.00%

    C12-TLRa is an adjuvant lipidoid.

  • GC71308 structure
    GC71308SARS-CoV-2-IN-41
    CAS: 2920904-06-7
    Purity: >99.00%

    SARS-CoV-2-IN-41 (compound 2) is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 value of 0.022 µM.

  • GC71314 structure
    GC71314DNA gyrase B-IN-2
    Purity: >99.00%

    DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens.

  • GC71318 structure
    GC71318BDM91270
    CAS: 2892824-11-0
    Purity: >99.00%

    BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB.

  • GC71319 structure
    GC71319ND-011992
    CAS: 2446880-46-0
    Purity: >98.00%

    ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases.

  • GC71324 structure
    GC71324SARS-CoV-2 3CLpro-IN-20
    CAS: 878985-00-3
    Purity: >97.00%

    SARS-CoV-2 3CLpro-IN-20 (Compound 5g) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.43 μM, Ki: 0.33 μM).

  • GC71332 structure
    GC71332Antimalarial agent 33
    Purity: >99.00%

    Antimalarial agent 33 (compound 5g) has antiplasmodial activity against erythrocytic and hepatic stages of Plasmodium with an EC50 of 1.1 μM for K1 P. falciparum strain.

  • GC71336 structure
    GC71336SHEN26
    CAS: 2691076-98-7
    Purity: >99.00%

    SHEN26 (ATY014) is a potent and orally active RdRp inhibitor, with an IC50 for SARS-CoV-2 is 1.36 μM.

  • GC71345 structure
    GC71345JC-229
    CAS: 3026716-22-0
    Purity: >97.00%

    JC-229 is a TbRPA1 inhibitor.