SARS-CoV
SARS-CoV (severe acute respiratory syndrome-cornavirus) is an enveloped positive-sense single-stranded RNA viruse that transmitted from human to human.
Products for SARS-CoV
- Cat.No. Product Name Information
- GC40559 (±)-Alliin Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor.
- GC40560 (+)-Alliin Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor.
- GC39317 (S)-Tenofovir (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir.
- GC61674 2-Hydroxyacetophenone 2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis.
- GC61753 2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia.
- GC35144 4'-O-Methylbavachalcone 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM.
- GC62354 Acriflavine hydrochloride Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid.
- GC60051 Anti-MERS-2E6 mAb Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.
- GC60052 Anti-MERS-3A1 mAb Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells.
- GC66241 Anti-MERS-D12 mAb Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12) is a human monoclonal IgG1. Anti-MERS-D12 mAb binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding.
- GC60054 Anti-SARS-80R mAb Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells.
- GC60055 Anti-SARS-CoV-2 Spike mAb (CR3022) Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody.
- GC60056 Anti-Spike-RBD mAb Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody.
- GC60057 Anti-Spike-RBD Single Domain mAb Anti-Spike-RBD Single Domain mAb is a CHO cell derived Alpaca monoclonal VHH-huFc antibody, specifically binds to SARS-CoV-2 RBD with high affinity.
- GC67913 Antiviral agent 5
- GC62320 AT-511 AT-511 (AT-511) is a potent and orally active HCV viral replication inhibitor.
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GC62321
AT-527
AT-527(Bemnifosbuvir hemisulfate), a hemisulfate salt of AT-511, a guanosine nucleotide proagent, is a potent and orally active HCV viral replication inhibitor.
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GC63412
AT-9010 tetrasodium
AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication).
- GC17903 Atovaquone unique naphthoquinone with broad-spectrum antiprotozoal activity
- GC65180 ATV006 ATV006 is a potent, orally active antiviral agent and ester prodrugs of GS-441524.
- GC60609 Aviptadil acetate Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects.
- GC46903 Azithromycin-d3 An internal standard for the quantification of azithromycin
- GC14250 Bepotastine Besilate Non-sedating, selective antagonist of histamine 1 (H1) receptor
- GC10959 Boceprevir An NS3/4A protease inhibitor
- GC46936 Boceprevir-d9 An internal standard for the quantification of boceprevir
- GC61885 Bonducellpin D Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax.
- GC15089 Carfilzomib (PR-171) A proteasome inhibitor
- GC63779 CCF0058981 CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CLpro (SC2) inhibitor with an IC50 of 68 nM.
- GC31707 Chebulagic acid Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis.
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GC19549
Chloroquine
An autophagy and toll-like receptors (TLRs) inhibitor
- GC60700 Chloroquine D5 Chloroquine D5 is deuterium labeled Chloroquine.
- GC10295 Chloroquine diphosphate Chloroquine diphosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis.
- GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine
- GC64289 Cichoriin Cichoriin is an active compounds against SARS-CoV-2, and may be a potential candidate in treating severe COVID-19.
- GC64264 Cleistanthin B Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside.
- GC12635 Clevudine antiviral drug
- GC12879 Danoprevir (RG7227) An HCV NS3/4A protease inhibitor
- GC17942 Darunavir Ethanolate nonpeptidic HIV protease inhibitor
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GC12828
Daunorubicin
DNA topoisomerase II inhibitor
- GC61677 Direct Violet 1 Direct Violet 1, an azo dye, is a textile dye.
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GC18620
EIDD-1931
A ribonucleoside analog with antiviral activity
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GC18413
EIDD-2801
An orally bioavailable prodrug of the ribonucleoside analog EIDD-1931
- GC64368 Ensitrelvir fumarate Ensitrelvir (S-217622) fumarate is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM).
- GC60856 FOY 251 FOY 251, an anti-proteolytic active metabolite Camostate, acts as a proteinase inhibitor.
- GC62221 GRL-0496 GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays.
- GC39172 GRL0617 A SARS-CoV and SARS-CoV-2 PLpro inhibitor
- GC63563 GS-621763 GS-621763, an orally bioavailable prodrug of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice.
- GC62414 HCoV-229E-IN-1 HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively.
- GC63500 HeE1-2Tyr HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor.
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GC12544
Hydroxychloroquine Sulfate
Autophagy inhibitor
- GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine
- GC60930 Imatinib D4 Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity.
- GC39612 Imatinib D8 Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity.
- GC43925 Ivermectin B1b Ivermectin B1b is the minor component.
- GC66366 Kansuinine B Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19.
- GC64263 Kobophenol A Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM.
- GC62667 KW-8232 KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.
- GC10317 Lamivudine Nucleoside analog reverse transcriptase inhibitor
- GC17439 Ledipasvir An HCV NS5A inhibitor
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GC69367
Lenzilumab
Lenzilumab (KB 003) is a humanized monoclonal antibody that targets CSF2/GM-CSF and can be used in research for COVID-19, chronic myelomonocytic leukemia (CMML), and juvenile myelomonocytic leukemia (JMML).
- GC13716 Lopinavir A potent HIV-1 protease inhibitor
- GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir
- GC63065 Merafloxacin Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses.
- GC63790 MERS-CoV-IN-1 MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.
- GC14363 Mitoxantrone HCl Mitoxantrone HCl is a potent topoisomerase II inhibitor.
- GC12301 Mizoribine DNA/RNA synthesis inhibitor
- GC39497 ML188 ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM.
- GC11655 Moexipril HCl Moexipril HCl (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride).
- GC62162 Molnupiravir Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931.
- GC67754 Molnupiravir-d7
- GC50727 MPro 13b MPro 13b is a potent Mpro inhibitor.
- GC47707 MPro Inhibitor 11a An inhibitor of SARS-CoV-2 Mpro
- GC47708 MPro Inhibitor 11b MPro Inhibitor 11b is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM.
- GC62208 Mpro inhibitor N3 hemihydrate Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2.
- GC50732 MPro N3
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GC69538
Narsoplimab
Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin G4 (IgG4) monoclonal antibody that binds to MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in hematopoietic stem cell transplantation and research on SARS-CoV-2.
- GC17709 Nelfinavir HIV-1 protease inhibitor
- GC61956 NHC-diphosphate NHC-diphosphate is an active phosphorylated?intracellular metabolite?of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form.
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GC61130
NHC-triphosphate
NHC-triphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form.
- GC61158 ONO-5334 ONO-5334 is a potent, selective and orally active cathepsin K inhibitor with Ki values of 0.10 nM, 0.049 nM and 0.85 nM for human, rabbit and rat cathepsin K, respectively.
- GC62133 PF-00835231 PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.
- GC62692 PF-07304814 PF-07304814 (PF-07304814), a phosphate prodrug of PF-00835231, acts as a potent 3CLproprotease (Mpro) inhibitor with SARS-CoV-2 antiviral activity.
- GC62631 PF-07321332 PF-07321332 (PF-07321332) is a potent and orally active SARS-CoV3C-like protease (3CLPRO) inhibitor.
- GC12116 Pitavastatin Calcium Enzyme HMGCR inhibitor
- GC36939 PLpro inhibitor PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC50 of 2.6 ?M.
- GC13197 Praziquantel anthelmintic
- GC37020 Prulifloxacin A prodrug from of ulifloxacin
- GC63782 RdRP-IN-2 RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor.
- GC62639 rel-Zotatifin rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A?inhibitor with activity less than Zotatifin.
- GC32223 Remdesivir (GS-5734) Remdesivir (GS-5734) (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively.
- GC25863 Riamilovir Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV.
- GC17303 Ritonavir An HIV protease inhibitor
- GC64331 Ritonavir-13C,d3
- GC16359 Rosuvastatin Competitive inhibitor of HMG-CoA reductase
- GC15736 Rosuvastatin Calcium HMG-CoA reductase inhibitor
- GC65943 SARS-CoV-2 3CLpro-IN-2 SARS-CoV-2 3CLpro-IN-2 (Compound 1) is a potent inhibitor of 3CL protease. SARS-CoV-2 3CLpro-IN-2 has the potential for the research of SARS-CoV-2 diseases.
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GC69861
SARS-CoV-2 nsp13-IN-1
SARS-CoV-2 nsp13-IN-1 (compound C1) is an effective inhibitor of nsp13 (non-structural protein 13). SARS-CoV-2 nsp13-IN-1 only inhibits the ssDNA+ ATPase activity of nsp13, with an IC50 of 6 μM. It does not inhibit ssDNA- ATPase activity. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research.
- GC67793 SARS-CoV-2-IN-13
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GC69860
SARS-CoV-2-IN-14
SARS-CoV-2-IN-14 (compound 6) is an effective inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. It is a chloronitroaniline analog. SARS-CoV-2-IN-14 has higher stability in human plasma and liver S9 enzyme assays compared to chloronitroaniline, and oral administration can improve its bioavailability and half-life.
- GC64011 SARS-CoV-2-IN-6 SARS-CoV-2-IN-6 is a SARS-CoV-2 3CLpro inhibitor that shows the most potent enzyme inhibitory IC50 value of 73 nM.