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Home >> Signaling Pathways >> Microbiology & Virology >> SARS-CoV

SARS-CoV

SARS-CoV (severe acute respiratory syndrome-cornavirus) is an enveloped positive-sense single-stranded RNA viruse that transmitted from human to human.

Products for  SARS-CoV

  1. Cat.No. Product Name Information
  2. GC40559 (±)-Alliin

    (±)-Allyl-L-cysteine sulfoxide

     Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. (±)-Alliin Chemical Structure
  3. GC40560 (+)-Alliin

    S-Allyl-L-cysteine sulfoxide

     Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. (+)-Alliin Chemical Structure
  4. GC39317 (S)-Tenofovir (S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. (S)-Tenofovir Chemical Structure
  5. GC71928 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one Chemical Structure
  6. GC71925 10-Hydroxyaloin A 10-10-Hydroxyaloin A is potent SARS-CoV-2 inhibitor. 10-Hydroxyaloin A Chemical Structure
  7. GC61674 2-Hydroxyacetophenone 2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis. 2-Hydroxyacetophenone Chemical Structure
  8. GC61753 2-Hydroxycinnamic acid 2-Hydroxycinnamic acid is isolated from the methanol extract of Cinnamomum cassia. 2-Hydroxycinnamic acid Chemical Structure
  9. GC35144 4'-O-Methylbavachalcone 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. 4'-O-Methylbavachalcone Chemical Structure
  10. GC62354 Acriflavine hydrochloride Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) is a fluorescent acridine dye that can be used to label nucleic acid. Acriflavine hydrochloride Chemical Structure
  11. GC72385 Adintrevimab Adintrevimab (ADG 20) is a human IgG1 monoclonal SARS-CoV (SARS-CoV) antibody. Adintrevimab Chemical Structure
  12. GC72389 Amubarvimab Amubarvimab (BRII-196) is a human IgG1 mAb that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein, with a KD of 5.88 nM. Amubarvimab Chemical Structure
  13. GC60051 Anti-MERS-2E6 mAb

    MERS-2E6; MERS Antibody-2E6

     Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells. Anti-MERS-2E6 mAb Chemical Structure
  14. GC60052 Anti-MERS-3A1 mAb

    MERS-3A1; MERS Antibody-3A1

     Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb Chemical Structure
  15. GC66241 Anti-MERS-D12 mAb

    MERS-D12; MERS Antibody-D12

     Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12) is a human monoclonal IgG1. Anti-MERS-D12 mAb binds directly to the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD) and effect neutralization by directly blocking receptor binding. Anti-MERS-D12 mAb Chemical Structure
  16. GC60054 Anti-SARS-80R mAb

    SARS-80R; SARS Antibody-80R

     Anti-SARS-80R mAb (SARS-80R) is a human monoclonal IgG1 antibody produced in CHO cells. Anti-SARS-80R mAb Chemical Structure
  17. GC60055 Anti-SARS-CoV-2 Spike mAb (CR3022)

    SARS-CR3022; SARS-CoV-2 Antibody-CR3022

     Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. Anti-SARS-CoV-2 Spike mAb (CR3022) Chemical Structure
  18. GC60056 Anti-Spike-RBD mAb

    SARS-CoV-2 (2019-nCoV) Spike RBD Antibody

     Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Anti-Spike-RBD mAb Chemical Structure
  19. GC60057 Anti-Spike-RBD Single Domain mAb

    SARS-CoV-2 (2019-nCoV) Single-Domain Antibodies; Humanized Single Domain Antibody

     Anti-Spike-RBD Single Domain mAb is a CHO cell derived Alpaca monoclonal VHH-huFc antibody, specifically binds to SARS-CoV-2 RBD with high affinity. Anti-Spike-RBD Single Domain mAb Chemical Structure
  20. GC67913 Antiviral agent 5 Antiviral agent 5 Chemical Structure
  21. GC73665 Arbemnifosbuvir

    AT-752 free base

     Arbemnifosbuvir is a nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12)-interfering drugs. Arbemnifosbuvir Chemical Structure
  22. GC62320 AT-511

    AT-511

     AT-511 (AT-511) is a potent and orally active HCV viral replication inhibitor. AT-511 Chemical Structure
  23. GC62321 AT-527

    Bemnifosbuvir hemisulfate

    AT-527(Bemnifosbuvir hemisulfate), a hemisulfate salt of AT-511, a guanosine nucleotide proagent, is a potent and orally active HCV viral replication inhibitor.

     AT-527 Chemical Structure
  24. GC63412 AT-9010 tetrasodium

    AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication).

     AT-9010 tetrasodium Chemical Structure
  25. GC17903 Atovaquone

    BW 566C, BW 556C-80

     unique naphthoquinone with broad-spectrum antiprotozoal activity Atovaquone Chemical Structure
  26. GC65180 ATV006

    ATV006

     ATV006 is a potent, orally active antiviral agent and ester prodrugs of GS-441524. ATV006 Chemical Structure
  27. GC14472 Aviptadil

    Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine)

     Aviptadil is a 28-amino acid neurotransmitter and a vasoactive intestinal polypeptide (VIP) analog. It has an effective vasodilator effect, can induce pulmonary vasodilation, and inhibit vascular smooth muscle cell proliferation and platelet aggregation. Aviptadil Chemical Structure
  28. GC60609 Aviptadil acetate Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate Chemical Structure
  29. GC46903 Azithromycin-d3 An internal standard for the quantification of azithromycin Azithromycin-d3 Chemical Structure
  30. GC68722 Bamlanivimab

    Anti-Human SARS-CoV-2

    Bamlanivimab (Anti-Human SARS-CoV-2) was the first COVID-19 monoclonal antibody (mAb) to receive emergency use authorization (EUA) from the US Food and Drug Administration (FDA) in November 2020. However, due to increasing resistance of the SARS-CoV-2 virus variants to Bamlanivimab, it was revoked in April 2021.

     Bamlanivimab Chemical Structure
  31. GC72334 Bebtelovimab Bebtelovimab a humanized IgG1-λ2 antibody targeting to SARS-CoV-2, especially COVID-19. Bebtelovimab Chemical Structure
  32. GC14250 Bepotastine Besilate

    Bepotastine besilate, TAU-284

     Non-sedating, selective antagonist of histamine 1 (H1) receptor Bepotastine Besilate Chemical Structure
  33. GC10959 Boceprevir

    Victrelis

     An NS3/4A protease inhibitor Boceprevir Chemical Structure
  34. GC46936 Boceprevir-d9 An internal standard for the quantification of boceprevir Boceprevir-d9 Chemical Structure
  35. GC61885 Bonducellpin D Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D Chemical Structure
  36. GC72395 Burfiralimab Burfiralimab (hzVSF-v13) is a monoclonal IgG4 antibody against vimentin expressed on the surface of virus-infected cells, with broad-spectrum antiviral activity and anti-inflammatory effects against virus-induced inflammation. Burfiralimab Chemical Structure
  37. GC15089 Carfilzomib (PR-171)

    PR-171

     A proteasome inhibitor Carfilzomib (PR-171) Chemical Structure
  38. GC68834 Casirivimab

    REGN10933

    Casirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus that causes COVID-19. Casirivimab lacks efficacy against COVID-19 variants. Casirivimab can be used in combination with Imdevimab to effectively reduce viral load and improve symptoms.

     Casirivimab Chemical Structure
  39. GC63779 CCF0058981

    CCF981

     CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CLpro (SC2) inhibitor with an IC50 of 68 nM. CCF0058981 Chemical Structure
  40. GC31707 Chebulagic acid Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid Chemical Structure
  41. GC19549 Chloroquine

    CHLORO QUINE PHOSPHATE; 4-(7-chloro-4-quinolylamino)pentyldiethylamine; (4S)-N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine

    An autophagy and toll-like receptors (TLRs) inhibitor

     Chloroquine Chemical Structure
  42. GC60700 Chloroquine D5 Chloroquine D5 is deuterium labeled Chloroquine. Chloroquine D5 Chemical Structure
  43. GC10295 Chloroquine diphosphate

    DL-Chloroquine, NSC 14050

     Chloroquine diphosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine diphosphate Chemical Structure
  44. GC45885 Chloroquine-d5 (phosphate)

    DL-Chloroquine-d5

     An internal standard for the quantification of chloroquine Chloroquine-d5 (phosphate) Chemical Structure
  45. GC64289 Cichoriin Cichoriin is an active compounds against SARS-CoV-2, and may be a potential candidate in treating severe COVID-19. Cichoriin Chemical Structure
  46. GC72412 Cilgavimab Cilgavimab (AZD-1061; COV2-2130) is a human SARS-CoV-2-neutralizing monoclonal antibody, can compose monoclonal-antibody combination AZD7442 with Tixagevimab . Cilgavimab Chemical Structure
  47. GC64264 Cleistanthin B Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B Chemical Structure
  48. GC12635 Clevudine

    Levovir, L-FMAU

     antiviral drug Clevudine Chemical Structure
  49. GC12879 Danoprevir (RG7227)

    ITMN-191, R-7227

     An HCV NS3/4A protease inhibitor Danoprevir (RG7227) Chemical Structure
  50. GC17942 Darunavir Ethanolate

    TMC114

     nonpeptidic HIV protease inhibitor Darunavir Ethanolate Chemical Structure
  51. GC12828 Daunorubicin

    DNA topoisomerase II inhibitor

     Daunorubicin Chemical Structure
  52. GC68939 Daxdilimab

    MEDI7734; VIB7734

    Daxdilimab is an anti-ILT7 monoclonal antibody, where ILT7 is a cell surface molecule specific to pDC-type dendritic cells. Daxdilimab can be used in the research of acute lung injury (ALI) caused by COVID-19 infection.

     Daxdilimab Chemical Structure
  53. GC61677 Direct Violet 1 Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 Chemical Structure
  54. GC18620 EIDD-1931

    β-D-N4-Hydroxycytidine, N4-Hydroxycytidine

    A ribonucleoside analog with antiviral activity

     EIDD-1931 Chemical Structure
  55. GC18413 EIDD-2801

    EIDD2801,EIDD 2801

    An orally bioavailable prodrug of the ribonucleoside analog EIDD-1931

     EIDD-2801 Chemical Structure
  56. GC64368 Ensitrelvir fumarate

    S-217622

     Ensitrelvir (S-217622) fumarate is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM). Ensitrelvir fumarate Chemical Structure
  57. GC70489 Fluphenazine-d8 Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine-d8 Chemical Structure
  58. GC60856 FOY 251 FOY 251, an anti-proteolytic active metabolite Camostate, acts as a proteinase inhibitor. FOY 251 Chemical Structure
  59. GC71871 Gallinamide A TFA Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM). Gallinamide A TFA Chemical Structure
  60. GC62221 GRL-0496 GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 Chemical Structure
  61. GC71247 GRL-1720 TFA GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 value of 15 μM. GRL-1720 TFA Chemical Structure
  62. GC39172 GRL0617 A SARS-CoV and SARS-CoV-2 PLpro inhibitor GRL0617 Chemical Structure
  63. GC63563 GS-621763

    GS-441524 tris-isobutyryl ester

     GS-621763, an orally bioavailable prodrug of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice. GS-621763 Chemical Structure
  64. GC62414 HCoV-229E-IN-1 HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively. HCoV-229E-IN-1 Chemical Structure
  65. GC63500 HeE1-2Tyr HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr Chemical Structure
  66. GC12544 Hydroxychloroquine Sulfate

    HCQ, NSC 4375

    Autophagy inhibitor

     Hydroxychloroquine Sulfate Chemical Structure
  67. GC47445 Hydroxychloroquine-d4 (sulfate)

    HCQ-d4

     An internal standard for the quantification of hydroxychloroquine Hydroxychloroquine-d4 (sulfate) Chemical Structure
  68. GC71397 Ibuzatrelvir Ibuzatrelvir (PF-07817883) is an antiviral agent, targeting to SARS-CoV-2 3CL protease. Ibuzatrelvir Chemical Structure
  69. GC60930 Imatinib D4 Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D4 Chemical Structure
  70. GC39612 Imatinib D8 Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D8 Chemical Structure
  71. GC69267 Imdevimab

    REGN10987

    Imdevimab (REGN10987) is a human monoclonal antibody that targets the SARS-CoV-2 virus causing COVID-19. Imdevimab lacks efficacy against COVID-19 variants. Imdevimab can be used in combination with Casirivimab to effectively reduce viral load and improve symptoms.

     Imdevimab Chemical Structure
  72. GC43925 Ivermectin B1b

    22,23-dihydro Avermectin B1b

     Ivermectin B1b is the minor component. Ivermectin B1b Chemical Structure
  73. GC73745 Jun12682 Jun12682 is an inhibitor of SARS-CoV-2 papain-like protease. Jun12682 Chemical Structure
  74. GC66366 Kansuinine B Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19. Kansuinine B Chemical Structure
  75. GC64263 Kobophenol A Kobophenol A, an oligomeric stilbene, blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. Kobophenol A Chemical Structure
  76. GC62667 KW-8232 KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2. KW-8232 Chemical Structure
  77. GC10317 Lamivudine

    (-)-BCH 189, 3TC, 2’,3’-dideoxy-3’-Thiacytidine

     Nucleoside analog reverse transcriptase inhibitor Lamivudine Chemical Structure
  78. GC17439 Ledipasvir

    GS-5885

     An HCV NS5A inhibitor Ledipasvir Chemical Structure
  79. GC69367 Lenzilumab

    KB 003

    Lenzilumab (KB 003) is a humanized monoclonal antibody that targets CSF2/GM-CSF and can be used in research for COVID-19, chronic myelomonocytic leukemia (CMML), and juvenile myelomonocytic leukemia (JMML).

     Lenzilumab Chemical Structure
  80. GC71221 Leritrelvir Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a Ki of 8.6 nM. Leritrelvir Chemical Structure
  81. GC13716 Lopinavir

    A157378.0, ABT378

     A potent HIV-1 protease inhibitor Lopinavir Chemical Structure
  82. GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir Lopinavir-d8 Chemical Structure
  83. GC71194 LY1 LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PLpro and Mpro with Kd values of 1.5 μM and 2.3 μM for Mpro C145A protein and PLpro C111A protein, respectively. LY1 Chemical Structure
  84. GC63065 Merafloxacin

    CI-934

     Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses. Merafloxacin Chemical Structure
  85. GC63790 MERS-CoV-IN-1 MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus. MERS-CoV-IN-1 Chemical Structure
  86. GC71631 Methylprednisolone-d7 Methylprednisolone-d7 is deuterium labeled Methylprednisolone. Methylprednisolone-d7 Chemical Structure
  87. GC14363 Mitoxantrone HCl

    NCI 301739, NSC 301739

     Mitoxantrone HCl is a potent topoisomerase II inhibitor. Mitoxantrone HCl Chemical Structure
  88. GC12301 Mizoribine

    NSC 289637

     DNA/RNA synthesis inhibitor Mizoribine Chemical Structure
  89. GC39497 ML188 ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. ML188 Chemical Structure
  90. GC11655 Moexipril HCl

    CI-925, RS 10085-197, SPM 925

     Moexipril HCl (RS-10085) is an orally active inhibitor of angiotensin-converting enzyme (ACE), and becomes effective by being hydrolyzed to moexiprila (hydrochloride). Moexipril HCl Chemical Structure
  91. GC62162 Molnupiravir

    EIDD-2801, β-D-N4-Hydroxycytidine-5′-isopropyl ester, MK-4482

     Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir Chemical Structure
  92. GC67754 Molnupiravir-d7

    EIDD-2801-d7; MK-4482-d7

     Molnupiravir-d7 Chemical Structure
  93. GC50727 MPro 13b MPro 13b is a potent Mpro inhibitor. MPro 13b Chemical Structure
  94. GC47707 MPro Inhibitor 11a An inhibitor of SARS-CoV-2 Mpro MPro Inhibitor 11a Chemical Structure
  95. GC47708 MPro Inhibitor 11b MPro Inhibitor 11b is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. MPro Inhibitor 11b Chemical Structure
  96. GC62208 Mpro inhibitor N3 hemihydrate Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate Chemical Structure
  97. GC50732 MPro N3 MPro N3 Chemical Structure
  98. GC69538 Narsoplimab

    OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)

     Narsoplimab (anti-MASP-2) is a human immunoglobulin gamma 4 (IgG4) monoclonal antibody against mannose-binding protein-associated serine protease 2 (MASP-2) achieved by high affinity (zymogen form: KD=0.062nM, IC50~3.4nM; enzymatically active form: KD=0.089nM) to block lectin pathway. Narsoplimab Chemical Structure
  99. GC17709 Nelfinavir HIV-1 protease inhibitor Nelfinavir Chemical Structure
  100. GC61956 NHC-diphosphate NHC-diphosphate is an active phosphorylated?intracellular metabolite?of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form. NHC-diphosphate Chemical Structure
  101. GC61130 NHC-triphosphate

    NHC-triphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form.

     NHC-triphosphate Chemical Structure

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