Microbiology & Virology

SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 (SARS-CoV-2 nsp3 macrodomain) inhibitor with the IC50 value of 6.1 μM.

Antimicrobial agent-8 (Compound 15) is a potent antimicrobial agent, and shows potent antimicrobial activity with an MIC range of 2-8 μg/mL against Gram-negative and Gram-positive bacteria.

BDM-2 is an IN-LEDGF allosteric inhibitor (INLAI) of HIV-1 integrase (IN refers to integrase) (IC50=47 nM) with potent anti-Retroviral (ARV) activity.

Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor.

SARS-CoV-2-IN-46 is a novel coronavirus (SARS-CoV-2) replication inhibitor with an EC50 of 0.9 μM in Calu-3 cells.

Antibiofilm agent-1 is an antibacterial agent that inhibits growth of Gram-positive pathogens (WO2017011725A1; compound 17).

Arbemnifosbuvir is a nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12)-interfering drugs.

Olgotrelvir sodium is an orally active dual inhibitor of coronavirus main protease (Mpro) and human cell cathepsin (Cathepsin L).

Jun12682 is an inhibitor of SARS-CoV-2 papain-like protease.

Antimalarial agent 38 exhibits activity against antiplasmodial, which inhibits Plasmodium falciparum D6 strain, chloroquine-sensitive Thai strain and chloroquine-resistant FcB1 strain and K1 strain, with IC50s of 0.5, 13, 1 and 13 μM, respectively.

Antiviral agent 55 (Compound 95) is an inhibitor for human immunodeficiency virus 1 and 2 (HIV 1 and HIV 2), and exhibits antiviral activity.

Aflatoxin B1/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria.

BAY 249716 stabilizes all three p53 protein variants.

Nipamovir is a nitroimidazole prodrug.

HN0037 is a selective and orally active helicase-primase inhibitor.

Lolamicin is a Gram-negative specific antibiotic.

HIV-1 inhibitor-69 (compound Test set 1) is a HIV-1 RT inhibitor.

Dimetl fumarate-d2 is the deuterium labeled Dimetl fumarate.

Itraconazole-d9 is the deuterium labeled Itraconazole.

BILB 1941 is a potent and specific nonnucleoside inhibitor of the hepatitis C virus (HCV) RNA polymerase in vitro.

GWP-042 is a potent inhibitor of mycobacterial alanine dedrogenase (Ald) Rv2780, with the IC50 of 0.21 μM.

trans-Clopenthixol ((E)-Clopenthixol) didrochloride is an antibiotic agent, without neuroleptic effect.

Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria.