GLPBio

Membrane Transporter/Ion Channel

Research Areas

Products Related to Membrane Transporter/Ion Channel(2345)

  • GC79405 structure
    GC79405TSLP modulator-1
    Purity: >99.50%

    TSLP modulator-1 (Compound 14O) is a potent TSLP signaling modulator.

  • GC79415 structure
    GC79415Afivastobart
    CAS: 3053974-60-7
    Purity: >99.00%

    Afivastobart (AB598) is a human ENTPD1 ( CD39 )-targeting monoclonal antibody with antineoplastic activity.Afivastobart binds as a monoclonal antibody to modulate Homo sapiens ENTPD1 activity.Afivastobart constitutes a glycoform alfa immunoglobulin G1-kappa monoclonal antibody [1] .

  • GC79485 structure
    GC79485Siaresinolic acid
    CAS: 511-77-3
    Purity: >98%

    Siaresinolic acid is a compound found in the leaves of Sabicea grisea.

  • GC79486 structure
    GC79486Bacoside A (mixture)
    Purity: >98.00%

    Bacoside A (mixture) is a mixture composed of Bacoside A3, Bacopaside II, Bacopaside X and Bacopasaponin C.

  • GC79487 structure
    GC79487(S)-Verapamil
    CAS: 36622-29-4
    Purity: >99.50%

    (S)-Verapamil ((S)-(-)-Verapamil) is an orally active MRP1 (ABCC1) modulator with a K d value of 113 nM for hamster MRP1.

  • GC79488 structure
    GC79488QBS10072S dihydrochloride
    CAS: 1802735-31-4
    Purity: >98%

    QBS10072S dihydrochloride is a LAT1 -selective substrate with blood-brain barrier permeability that inhibits tumor growth.

  • GC79489 structure
    GC79489SRA-36
    Purity: >99.50%

    SRA-36 is a CLC-K chloride channel inhibitor with selectivity over CLC-5 and CLC-1 chloride channels.

  • GC79490 structure
    GC79490Cerebellin TFA
    Purity: >95.00%

    Cerebellin TFA is a neuromodulatory hexadecapeptide that serves as a marker for Purkinje cell maturation.

  • GC79491 structure
    GC79491UK-78282
    CAS: 191217-42-2
    Purity: >98%

    UK-78282 is a K V 1.3 channel inhibitor with an IC 50 value of 0.20 μM and a K d of 0.39 μM.

  • GC79492 structure
    GC79492ML077
    CAS: 1135304-61-8
    Purity: >98%

    ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 ( KCC2 ) with an IC 50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak ( IC 50 > 50 μM).

  • GC79493 structure
    GC79493F3288-0031
    CAS: 926493-93-8
    Purity: >98%

    F3288-0031 is a brain-penetrant norepinephrine transporter ( NET ) allosteric inhibitor with inhibitory rates of 73.5% at 20 μM.

  • GC79494 structure
    GC79494ATPase-IN-7
    CAS: 816450-73-4
    Purity: >99.50%

    ATPase-IN-7 (Example 1) is a H + /K + -ATPase inhibitor.

  • GC79495 structure
    GC79495slCeMM1
    CAS: 949973-22-2
    Purity: >98%

    slCeMM1 is a selective SLC16A3 ( MCT4 ) inhibitor.

  • GC79496 structure
    GC79496NS-6740
    CAS: 753500-02-6
    Purity: >99.50%

    NS-6740 is a silent agonist of α7 nicotinic acetylcholine receptor ( α7 nAChR ) with an IC 50 of 3 nM.

  • GC79497 structure
    GC79497Pincainide
    CAS: 83471-41-4
    Purity: >98.00%

    Pincainide is a calcium channel inhibitor.

  • GC79498 structure
    GC79498Calciseptine TFA
    Purity: >97.50%

    Calciseptine TFA, a polypeptide found in black mamba venom, is a selcetive Cav1.2 L-type calcium channel inhibitor with an IC 50 of 92 nM.

  • GC79499 structure
    GC79499RyR1-IN-1
    CAS: 2837939-81-6
    Purity: >98%

    RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC 50 of 12 nM.

  • GC79500 structure
    GC79500OV329 hydrochloride
    CAS: 2093928-29-9
    Purity: >99.50%

    OV329 hydrochloride is a potent GABA aminotransferase inactivator.

  • GC79501 structure
    GC79501GABA-palmitamide
    CAS: 58725-44-3
    Purity: >98.50%

    GABA-palmitamide is a GABA-responsive compound.

  • GC79502 structure
    GC79502mNLS-CPP-WSTF TFA
    Purity: >96.00%

    mNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF.

  • GC79503 structure
    GC79503mNLS-CPP-scramble TFA
    Purity: >98.00%

    mNLS-CPP-scramble (TFA) is the trifluoroacetate salt of mNLS-CPP-scramble.

  • GC79504 structure
    GC79504(R)-Verapamil
    CAS: 38321-02-7
    Purity: >98.50%

    (R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil.

  • GC79505 structure
    GC79505RPI-GLYT2-82
    Purity: >99.00%

    RPI-GLYT2-82 is a reversible, blood-brain barrier-permeable allosteric inhibitor of GlyT2 with an IC 50 value of 554 nM.

  • GC79506 structure
    GC79506Blixeprodil hydrochloride
    CAS: 3048183-44-1
    Purity: >97.00%

    Blixeprodil hydrochloride (GM-1020 hydrochloride) is an orally active, blood-brain barrier-penetrant NMDA receptor inhibitor with a K i of 3.25 µM in rat cortical tissues.