Membrane Transporter/Ion Channel
Research Areas
- AMPAR(55)
- Aquaporins(3)
- Piezo Channels(6)
- ATPase(77)
- Calcium Channel(342)
- Cannabinoid Transporters(6)
- CFTR(49)
- Chloride Channels(12)
- GABA Receptor(191)
- Gardos Channel
- Glucose Transporters(17)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(30)
- Kv1.3
- ICB(1)
- Lipophilic platinum complex
- M2 ion Channel
- MCT2(2)
- Monoamine transporter(16)
- Monocarboxylate Transporters(14)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(16)
- NKCC(8)
- NMDA Receptor(77)
- Nucleoside Transporters(5)
- Pannexin-1(2)
- P2X purinergic receptor(69)
- P-gp(10)
- Proton Pump(58)
- Potassium Channel(323)
- Sodium Channel(215)
- TRP Channel(184)
- TRPV1(10)
- URAT1(14)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(11)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(29)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(9)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(30)
- P-glycoprotein(55)
- iGluR(171)
- nAChR(110)
- VDAC(3)
- GlyR(1)
- Ferroportin(4)
- Urea Transporter(1)
- Na+/H+ Exchanger (NHE)(2)
- NTPDase(3)
- EAAT(5)
- ASCT(3)
- Apical Sodium-Dependent Bile Acid Transporter(1)
- Sec61(2)
- ATP-binding cassette (ABC) transporters(4)
- SLC39 (Zinc Transporter)(1)
- Sodium Phosphate Cotransporter(1)
Products Related to Membrane Transporter/Ion Channel(2345)
- GC79508GluN2B-NMDAR Allosteric modulator 1CAS: 2419700-58-4Purity: >99.50%
GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator.
- GC79510AMPA receptor modulator-10CAS: 620940-01-4Purity: >98.50%
AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator.
- GC79511JNJ-78911118CAS: 3106013-91-3Purity: >99.00%
JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist ( IC 50 = 44 nM).
- GC79512Sepimostat trifluoroacetatePurity: >99.50%
Sepimostat (FUT-187) trifluoroacetate exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit.
- GC79514(S)-6-MethylnicotineCAS: 13270-56-9Purity: >98.00%
(S)-6-Methylnicotine is a nicotinic acetylcholine receptor ( nAChR ) agonist that exhibits agonistic activity on isolated guinea pig ileum.
- GC79515HydrohydrastinineCAS: 494-55-3Purity: >99.50%
Hydrohydrastinine is a selective α4β2 nicotinic acetylcholine receptor antagonist with an IC 50 of 2.6 μM and a K i of 17 μM.
- GC79516nAChR antagonist 3CAS: 3114746-65-2Purity: >98%
nAChR antagonist 3 is a selective α7 nAChR antagonist with an IC 50 of 0.86 μM.
- GC79518Spinosyn LCAS: 149092-01-3Purity: >98.00%
Spinosyn L is a selective nicotinic acetylcholine receptors ( nAChR ) agonist.
- GC79520Nav1.2-IN-2CAS: 7469-49-0Purity: >99.50%
Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC 50 of 0.18 μM.
- GC79521CAD204520 dihydrochlorideCAS: 2682205-21-4Purity: >99.00%
CAD204520 dihydrochloride, a SERCA inhibitor ( IC 50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).
- GC79522TRPA1 agonist-3CAS: 3083086-77-2Purity: >99.50%
TRPA1 agonist-3 is a selective and orally active TRPA1 agonist, with EC 50 values of 50.05 μM and 314.04 μM for human and mouse TRPA1, respectively.
- GC79523IndazapyroxametCAS: 1689545-27-4Purity: >98%
Indazapyroxamet is an orally active insect TRPV channel (Nan/Iav subunit) modulator and insecticide.
- GC79525TRPM3-IN-1CAS: 2776193-88-3Purity: >98.00%
TRPM3-IN-1 (compound 124) is an inhibitor of TRPM3 with an IC 50 value <1 µM.
- GC79529TRPC3 agonist-1CAS: 1589567-51-0Purity: >99.50%
TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79507 | PSB-12054 | 1407632-07-8 | >98.50% | |
PSB-12054 is a P2X4 receptor antagonist with IC 50 values of 0.19 μM, 2.10 μM and 1.77 μM against human, rat and mouse receptors, respectively, and exhibits selectivity over other human P2X receptor subtypes. | ||||
| GC79508 | GluN2B-NMDAR Allosteric modulator 1 | 2419700-58-4 | >99.50% | |
GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator. | ||||
| GC79509 | UCM-A86 | 1210899-51-6 | >98.50% | |
UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively. | ||||
| GC79510 | AMPA receptor modulator-10 | 620940-01-4 | >98.50% | |
AMPA receptor modulator-10 (Compound 9a) is an orally active AMPA receptor ( AMPAR ) positive allosteric modulator. | ||||
| GC79511 | JNJ-78911118 | 3106013-91-3 | >99.00% | |
JNJ-78911118 is a potent, brain-penetrant, selective GluN2A antagonist ( IC 50 = 44 nM). | ||||
| GC79512 | Sepimostat trifluoroacetate | - | >99.50% | |
Sepimostat (FUT-187) trifluoroacetate exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. | ||||
| GC79513 | Lemairamin | 29946-61-0 | >99.50% | |
Lemairamin (Wgx-50) is a hydroxylamine compound. | ||||
| GC79514 | (S)-6-Methylnicotine | 13270-56-9 | >98.00% | |
(S)-6-Methylnicotine is a nicotinic acetylcholine receptor ( nAChR ) agonist that exhibits agonistic activity on isolated guinea pig ileum. | ||||
| GC79515 | Hydrohydrastinine | 494-55-3 | >99.50% | |
Hydrohydrastinine is a selective α4β2 nicotinic acetylcholine receptor antagonist with an IC 50 of 2.6 μM and a K i of 17 μM. | ||||
| GC79516 | nAChR antagonist 3 | 3114746-65-2 | >98% | |
nAChR antagonist 3 is a selective α7 nAChR antagonist with an IC 50 of 0.86 μM. | ||||
| GC79517 | RGH-857 | 2408754-53-8 | >98.00% | |
RGH-857 is an orally active, selective, potent nicotinic α7 positive allosteric modulator. | ||||
| GC79518 | Spinosyn L | 149092-01-3 | >98.00% | |
Spinosyn L is a selective nicotinic acetylcholine receptors ( nAChR ) agonist. | ||||
| GC79519 | SKF-96365 | 162849-90-3 | >99.50% | |
SKF-96365 is a TRPC channel antagonist and store-operated calcium entry ( SOCE ) inhibitor. | ||||
| GC79520 | Nav1.2-IN-2 | 7469-49-0 | >99.50% | |
Nav1.2-IN-2 is a Nav1.2 inhibitor with a human IC 50 of 0.18 μM. | ||||
| GC79521 | CAD204520 dihydrochloride | 2682205-21-4 | >99.00% | |
CAD204520 dihydrochloride, a SERCA inhibitor ( IC 50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL). | ||||
| GC79522 | TRPA1 agonist-3 | 3083086-77-2 | >99.50% | |
TRPA1 agonist-3 is a selective and orally active TRPA1 agonist, with EC 50 values of 50.05 μM and 314.04 μM for human and mouse TRPA1, respectively. | ||||
| GC79523 | Indazapyroxamet | 1689545-27-4 | >98% | |
Indazapyroxamet is an orally active insect TRPV channel (Nan/Iav subunit) modulator and insecticide. | ||||
| GC79524 | ADM 12 | 1644134-60-0 | >98.50% | |
ADM 12 is a highly selective transient receptor potential ankyrin 1 ( TRPA1 ) channel antagonist. | ||||
| GC79525 | TRPM3-IN-1 | 2776193-88-3 | >98.00% | |
TRPM3-IN-1 (compound 124) is an inhibitor of TRPM3 with an IC 50 value <1 µM. | ||||
| GC79526 | AM-0883 | - | >98.50% | |
AM-0883 is a TRPC6 (Transient receptor potential canonical 6) agonist ( hTRPC6 EC 50 = 46 nM). | ||||
| GC79527 | AMG-8562 | 1041478-78-7 | >98% | |
AMG-8562 is a selective, orally active transient receptor potential vanilloid 1 ( TRPV1 ) modulator that inhibits the activation of rat TRPV1 by Capsaicin, Anandamide and N-arachidonyldopamine, with IC 50 values of 1.75, 9.29 and 3.87 nM, respectively. | ||||
| GC79528 | ZA18 | 2696407-32-4 | >99.50% | |
ZA18 is a selective TRPM2 channel inhibitor, with an IC 50 value of 6.2 μM. | ||||
| GC79529 | TRPC3 agonist-1 | 1589567-51-0 | >99.50% | |
TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist. | ||||
| GC79530 | Trpvicin | 2019994-90-0 | >98.00% | |
Trpvicin is a potent and subtype-selective TRPV3 inhibitor with IC 50 s of 0.41 and 0.22 μM for hTRPV3-WT and hTRPV3-G573S mutant, respectively. | ||||