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Membrane Transporter/Ion Channel

Research Areas

Products Related to Membrane Transporter/Ion Channel(2345)

  • GC81683 structure
    GC81683AM9053
    CAS: 157469-21-1
    Purity: >98.00%

    AM9053 is a selective, effective and slowly reversible inhibitor of N-acyl ethanolamine acid amidease ( NAAA ) ( IC 50 = 30 nM).

  • GC81696 structure
    GC81696Hepcidin antagonist-1
    CAS: 338965-09-6
    Purity: >98.00%

    Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC 50 <50 μM.

  • GC81721 structure
    GC81721Ivabradine
    CAS: 155974-00-8
    Purity: >99.50%

    Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If).

  • GC81722 structure
    GC81722pan-HCN-IN-1
    CAS: 1334308-63-2
    Purity: >99.50%

    pan-HCN-IN-1 is a potent HCN ion channel inhibitor with IC 50 values of 58 nM, 522 nM, 58 nM, and 58 nM against HCN1, HCN2, HCN3, and HCN4, respectively.

  • GC81723 structure
    GC81723Saviprazole
    CAS: 121617-11-6
    Purity: >96.00%

    Saviprazole (HOE-731) is a H +,K + -ATPase inhibitor.

  • GC81724 structure
    GC81724Pyrimidinone 8
    CAS: 65004-42-4
    Purity: >99.50%

    Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 ( DMT1 ), with a K i of 20 μM ( hDMT1 ).

  • GC81725 structure
    GC81725TRPV1 antagonist 10
    CAS: 896584-55-7
    Purity: >98.50%

    TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist ( IC 50 = 33.06 nM), moderate to weak URAT1 ( IC 50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor.

  • GC81726 structure
    GC81726VUANT1
    CAS: 663212-40-6
    Purity: >98.50%

    VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling.

  • GC81728 structure
    GC81728TTFB
    CAS: 352560-76-0
    Purity: >98.00%

    TTFB (N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide) is a selective, non-competitive zinc-activated channel ( ZAC ) antagonist.

  • GC81734 structure
    GC81734UCB1244283
    CAS: 300587-89-7
    Purity: >99.50%

    UCB1244283 is a synaptic vesicle glycoprotein 2A ( SV2A ) allosteric modulator.

  • GC81738 structure
    GC81738URAT1 inhibitor 7
    CAS: 1632002-28-8
    Purity: >98.00%

    URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC 50 of 12 nM.

  • GC81764 structure
    GC81764ABC transporter modulator-1
    CAS: 3093661-22-1
    Purity: >96.00%

    ABC transporter modulator-1 (Compound I-5) is an ABC transporter expression enhancer.

  • GC81765 structure
    GC81765ABC transporter modulator-2
    CAS: 3093663-15-8
    Purity: >96.00%

    ABC transporter modulator-2 (Compound I-200) is a ABC transporter expression modulator.

  • GC81766 structure
    GC81766ABC transporter modulator-3
    CAS: 3093661-88-9
    Purity: >97.00%

    ABCC6 modulator-3 (Compound I-71) is a ABCC6 activator with an EC 50 < 1 μM.

  • GC81824 structure
    GC81824(+)-Talinolol
    CAS: 71369-60-3
    Purity: >99.00%

    (+)-Talinolol is an isomer of Talinolol.

  • GC81838 structure
    GC81838ICA604025
    Purity: >98%

    ICA604025 is a state-dependent inhibitor of human Nav1.9 voltage-gated sodium channel.

  • GC81852 structure
    GC81852Piezo1 agonist 2 hydrochloride
    Purity: >98.50%

    Piezo1 agonist 2 hydrochloride is a blood-brain barrier-permeable Piezo1 agonist and Jedi2 conjugate that utilizes LAT1.

  • GC81884 structure
    GC81884(R)-Vanzacaftor-d₄
    Purity: >98.00%

    (R)-Vanzacaftor -d 4 ((R)-VX-121-d 4 ) is the deuterated-labeled (R)-Vanzacaftor.

  • GC90516 structure
    GC90516VK-II-86
    CAS: 955371-84-3
    Purity: >90.00%

    مثبط لـ SOICR

  • GC90815 structure
    GC908152',3'-cyclic NADP+ (sodium salt)
    CAS: 100929-77-9
    Purity: >95.00%

    مادة أساسية لـ CNP

  • GC90867 structure
    GC908678-bromo NAD+ (sodium salt)
    CAS: 2022926-16-3
    Purity: >95.00%

    صيغة برو-دواء لـ 8-bromo-cADPR

  • GC90919 structure
    GC90919Guanosine 5'-[γ-thio]triphosphate (sodium salt)
    CAS: 1486471-09-3
    Purity: >95.00%

    ترجمة: عنصر تشابهي لـ GTP مقاوم لعملية التحلل المائي.

  • GC91153 structure
    GC91153Sulfonadyn-47
    Purity: >98.00%

    مثبط داينامين

  • GC91590 structure
    GC91590DTPD-Q
    CAS: 252950-56-4
    Purity: >98.00%

    DTPD-Q is an oxidized derivative of the antioxidant and methylphenyl substituted p-phenylenediamine DTPD.