GLPBio

DNA Damage/DNA Repair

Research Areas

Products Related to DNA Damage/DNA Repair(2183)

  • GC74250 structure
    GC74250Thymidine-13C10,15N2
    CAS: 1821188-00-4
    Purity: >99.00%

    Thymidine-13C10,15N2は13 Cと15 NマークのTmidineです。

  • GC74261 structure
    GC74261(R)-(+)-O-Demethylbuchenavianine
    CAS: 1364123-68-1
    Purity: >98.00%

    (R)-(+)-O-Demethylbuchenavianineは、細胞周期タンパク質依存性キナーゼCDKの阻害剤である。

  • GC74262 structure
    GC74262(S)-(-)-O-Demethylbuchenavianine
    CAS: 91147-18-1

    (S)-(-)-O-Demethylbuchenavianine（化合物（S）−（−）−1）はフラボノイドアルカロイドである。

  • GC74316 structure
    GC74316ATR kinase substrate peptide
    Purity: >99.00%

    ATR kinase substrate peptide (compound 45)は、atr (ataxia telangiectasia and rad3 related)プロテインキナーゼ(ki =6 nm)の強力かつ選択的阻害剤です。

  • GC74324 structure
    GC74324Cdk5i peptide
    CAS: 2298317-00-5
    Purity: >99.00%

    Cdk5i peptideはcdk5由来の12アミノ酸ペプチド断片である。

  • GC74652 structure
    GC74652Exatecan Intermediate 2 hydrochloride
    CAS: 2437603-23-9
    Purity: >99.00%

    Exatecan Intermediate 2 hydrochloride（化合物B）はExatecan（DX-8951）の中間体である。

  • GC74653 structure
    GC74653Exatecan Intermediate 4
    CAS: 2436720-50-0

    Exatecan Intermediate 4 (b)はエキサテカン(dx-8951)の中間体である。

  • GC74654 structure
    GC74654Exatecan Intermediate 4 dihydrochloride
    Purity: >99.00%

    Exatecan Intermediate 4 dihydrochlorideはExatecan（DX-8951）の中間体である。

  • GC74656 structure
    GC74656Topoisomerase IIα-IN-8
    CAS: 1251578-67-2

    Topoisomerase IIα-IN-8(複合15日)のDNAは弱い人間DNAトポイソメラーゼIIa (htIIa)剤のIC50 462±38.0μM。

  • GC74684 structure
    GC74684Topoisomerase II inhibitor 14
    CAS: 305343-00-4
    Purity: >99.00%

    Topoisomerase II inhibitor 14（化合物2 f）はトポロジイソメラーゼIIの強力な阻害剤であり、抗がん活性を有する。

  • GC74712 structure
    GC74712N-6-Methyl-2-deoxyadenosine-d3
    CAS: 1354782-02-7
    Purity: >99.00%

    N-6-Methyl-2-deoxyadenosine-d3は重水素標識N-6-Mell-2-デオキシアデノシンである。

  • GC74727 structure
    GC74727JSH-009
    CAS: 2247481-08-7

    JSH-009は、転写伸長の調節に重要な新規の高選択的cdk9阻害剤である。

  • GC74733 structure
    GC74733Methoxyamine-d3 Hydrochloride
    CAS: 110220-55-8
    Purity: >99.00%

    Methoxyamine-d3 Hydrochloride (o-metldroxylamine-d3)はメトキサミンドロクロライドの重水素である。

  • GC75685 structure
    GC75685PolQi1
    CAS: 2607139-80-8
    Purity: >98.00%

    PolQi1 is a selective inhibitor targeting the structure domain of DNA polymerase Polθ.

  • GC75826 structure
    GC75826YL-5092
    CAS: 3056857-07-6
    Purity: >98.00%

    YL-5092 is a novel, highly selective inhibitor of YTHDC1 (IC 50 =7.4nM; K D =29.6nM).

  • GC78755 structure
    GC78755ZW-251
    Purity: >98.00%

    ZW-251 is a glypican-3 ( GPC3 )-targeted antibody-drug conjugate ( ADC ) with topoisomerase-I inhibitory activity.

  • GC78756 structure
    GC78756Mocertatug rezetecan (DAR4)
    CAS: 3042848-25-6
    Purity: >98.00%

    Mocertatug rezetecan (DAR4) (HS-20089 (DAR4); GSK5733584 (DAR4)) is an antibody-drug conjugate ( ADC ) targeting B7-H4, composed of Mocertatug and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan.

  • GC78757 structure
    GC78757Mocertatug rezetecan (DAR6)
    CAS: 3042848-25-6
    Purity: >98.00%

    Mocertatug rezetecan (DAR6) (HS-20089 (DAR6); GSK5733584 (DAR6)) is an antibody-drug conjugate ( ADC ) targeting B7-H4, composed of Mocertatug and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan.

  • GC78759 structure
    GC787592-MSP-5-HA-VA-PAB-Exatecan
    CAS: 2878440-72-1
    Purity: >97.50%

    2-MSP-5-HA-Val-Cit-PAB-Exatecan (A-24) is a drug-linker conjugate for ADC.

  • GC78760 structure
    GC787602-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan
    CAS: 3115661-30-5
    Purity: >97.50%

    2-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan is a Drug-linker conjugates for ADC consisting of the ADC Cytotoxin Exatecan and a linker.

  • GC78761 structure
    GC78761BLD1102
    CAS: 3025473-38-2
    Purity: >99.50%

    BLD1102 is a linker-load conjugate ( Drug-Linker Conjugates for ADC ) consisting of a DNA topoisomerase I inhibitor BCPT02 and a protease-cleavable linker.

  • GC78766 structure
    GC78766N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan)
    Purity: >98.00%

    N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan, and an ADC linker composition.

  • GC78767 structure
    GC78767N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)
    Purity: >98.00%

    N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan, and an ADC linker composition.

  • GC78795 structure
    GC78795DBCO-PEG3-GGFG-Exatecan
    CAS: 2754384-71-7
    Purity: >95.50%

    DBCO-PEG3-GGFG-Exatecan is a Drug-linker conjugate for ADC.