Ubiquitination/ Proteasome

VISTA-IN-2 (Compound 1) is an inhibitor of V-domain Ig suppressor of T-cell activation (VISTA).

PIK5-12d is a PROTAC PIKfyve degrader (DC50: 1.48 nM).

FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM.

ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage.

ARI-3144 is an excellent substrate for fibroblast activation protein (FAP).

DCC-3116 is an orally active ULK1/2 inhibitor.

PHTPP-1304 is a PHTPP-based autophagy targeting chimera (AUTOTAC) that induces p62 self-oligomerization and degradation of estrogen receptor ERβ (DC50:~2 nM, HEK293T).

Fumagilin-105 is an autophagy targeting chimera (AUTOTAC) that induces p62 self-oligomerization with DC50 values of 0.7 μM for MetAP2 in HEK293 cells.

AUTAC2-2G is a second-generation AUTAC with a 100-fold increase in activity.

ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively.

ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM.

Dimetl fumarate-d2 is the deuterium labeled Dimetl fumarate.

Itraconazole-d9 is the deuterium labeled Itraconazole.

Salicylic acid-13C6 is the 13C-labeled Salicylic acid.

PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation.

3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs).

STK683963 is a strong activator of cellular ATG4B activity.

(2S,3R,4S)-ASX-173 is the (2S,3R,4S)-enantiomer of ASX-173.

DMBP is a VPS41 inhibitor.

T1742 is an autophagy inhibitor targeting ATG5.

C18-Pyr-Cer is a chemically modified synthetic ceramide analog.

Autophagy-IN-8 is an autophagy inhibitor.

Autophagy-IN-8 (DQ 660) hydrochloride is an autophagy inhibitor with antiproliferative activity against cancer cells.

YLDLAPL is a sleep-enhancing peptide that can be isolated from truffle albumin hydrolysate.