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Home >> Signaling Pathways >> Ubiquitination/ Proteasome >> p97

p97

p97 is a AAA-type ATPase that involved in mitosis-related events, such as golgi stacks fragmentation, tER formation, spindle pole body function and homotypic membrane fusion etc.

Products for  p97

  1. Cat.No. Product Name Information
  2. GC16351 CB-5083

    p97 inhibitor

     CB-5083 Chemical Structure
  3. GC20117 CB-5339

    CB-5339 is a second generation, potent and selective, orally bioavailable, ATP-competitive, small molecule inhibitor of valosin containing protein (VCP)/p97 [1,2].

     CB-5339 Chemical Structure
  4. GC10824 DBeQ P97 ATPase inhibitor DBeQ Chemical Structure
  5. GC14059 ML 240 ATP-competitive inhibitor of p97 ATPase ML 240 Chemical Structure
  6. GC11749 ML241 p97 ATPase inhibitor ML241 Chemical Structure
  7. GC13656 ML241 hydrochloride p97 ATPase inhibitor ML241 hydrochloride Chemical Structure
  8. GC10048 MNS Inhibitor of Src/Syk tyrosine kinases MNS Chemical Structure
  9. GC60257 MSC1094308 MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a drugable hotspot of p97. MSC1094308 can be used in study of cancer. MSC1094308 Chemical Structure
  10. GC32874 NMS-859 NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. NMS-859 Chemical Structure
  11. GC17250 NMS-873 VCP/p97 inhibitor,selective and allosteric NMS-873 Chemical Structure
  12. GC64694 UPCDC-30245 UPCDC-30245 is an allosteric p97 inhibitor with an IC50 of approximately 27 nM. UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC50=300 nM) and shows 3-fold resistance for p97 mutant T688A. UPCDC-30245 can be used in the research of cancer. UPCDC-30245 Chemical Structure

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