16-epi Latrunculin B |
رقم الكتالوجGC41110 |
16-epi Latrunculin B, first isolated from the Red Sea sponge N.
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Cas No.: 444911-05-1
Sample solution is provided at 25 µL, 10mM.
16-epi Latrunculin B, first isolated from the Red Sea sponge N. magnifica, is a stereoisomer of the actin polymerization inhibitor, latrunculin B . At 5-10 µg/ml, 16-epi latrunculin B can disrupt microfilament activity in an actin disruption assay. It also demonstrates cytotoxic activity in mouse KA31T and NIH3T3 tumor cells (GI50s = 1 and 4 µg/ml, respectively) and antiviral activity against herpes simplex type 1 virus (ED50 = 1 µg/ml).
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