(1S)-Calcitriol (Synonyms: 1α,25-Dihydroxy-3-epi-vitamin-D3) |
| رقم الكتالوجGC62730 |
(1S) -Calcitriol (1α ، 25-Dihydroxy-3-epi-vitamin-D3) هو مستقلب طبيعي لـ 1α ، 25-dihydroxyvitamin D3 (1α ، 25 (OH) 2D3)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 61476-45-7
Sample solution is provided at 25 µL, 10mM.
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(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].
3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1].
[1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114(10):2293-305.
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