2-Aminoquinoline |
| رقم الكتالوجGC64739 |
2-Aminoquinoline (2-Quinolinamine) هو مركب واعد كمثبط لـ nNOS متوفر بيولوجيًا ولكنه يعاني من انخفاض تثبيط nNOS البشري ، والانتقائية المنخفضة مقابل eNOS البشري ، والارتباط الكبير بأهداف الجهاز العصبي المركزي الأخرى
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 580-22-3
Sample solution is provided at 25 µL, 10mM.
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2-Aminoquinoline is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1].
[1]. Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60(16):7146-7165.
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