2-Deoxy-D-glucose 6-phosphate disodium |
| رقم الكتالوجGC62773 |
يتم إنتاج 2-Deoxy-D-glucose 6-phosphate disodium ، وهو مشتق من 2-Deoxy-D-glucose ، في خلايا الثدييات عن طريق عمل hexokinase على 2-DG
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Cas No.: 33068-19-8
Sample solution is provided at 25 µL, 10mM.
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2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].
[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.
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