الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>3-Phenoxybenzoic acid-13C6

3-Phenoxybenzoic acid-13C6

رقم الكتالوجGC72556 Copy One-Click Copy Product Info

3-Phenoxybenzoic acid-13C6 هو 13C6 المسمى 3-Phenoxybenzoic.

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3-Phenoxybenzoic acid-13C6 التركيب الكيميائي

Cas No.: 1793055-05-6

الحجم السعر المخزون الكميّة
1 mg
608٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of 3-Phenoxybenzoic acid-13C6

3-Phenoxybenzoic acid-13C6 is the 13C6 labeled 3-Phenoxybenzoic acid. 3-Phenoxybenzoic acid is an endogenous metabolite.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical Properties of 3-Phenoxybenzoic acid-13C6

Cas No. 1793055-05-6 SDF
Formula C713C6H10O3 M.Wt 220.17
الذوبان Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 3-Phenoxybenzoic acid-13C6

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.5419 mL 22.7097 mL 45.4194 mL
5 mM 908.4 μL 4.5419 mL 9.0839 mL
10 mM 454.2 μL 2.271 mL 4.5419 mL
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In vivo Formulation Calculator (Clear solution) of 3-Phenoxybenzoic acid-13C6

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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