4'-Aminomethyl-4,5',8-trimethylpsoralen (Synonyms: 4'-Aminomethyltrioxsalen) |
| رقم الكتالوجGC42339 |
4'-Aminomethyl-4,5',8-trimethylpsoralen is a bifunctional photoreactive agent for crosslinking nucleic acids.
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Cas No.: 64358-50-5
Sample solution is provided at 25 µL, 10mM.
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4'-Aminomethyl-4,5',8-trimethylpsoralen is a bifunctional photoreactive agent for crosslinking nucleic acids. In the dark, it intercalates into double-stranded regions in DNA or RNA. Upon long wavelength UV irradiation (e.g., 365 nm), 4'-aminomethyl-4,5',8-trimethylpsoralen first forms a covalent monoadduct with a pyrimidine base, followed by covalently linking with an adjacent pyrimidine on the opposite strand. Short wavelength UV irradiation (e.g., 254 nm) reverses this reaction. 4'-Aminomethyl-4,5',8-trimethylpsoralen has a high binding affinity for RNA and has been used to study different types of RNA from diverse organisms, including viruses.
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