الصفحة الرئيسية>>Analytical Standards>>6-keto Prostaglandin F1α-d4

6-keto Prostaglandin F1α-d4 (Synonyms: 6keto PGF1αd4)

رقم الكتالوجGC18841 Copy One-Click Copy Product Info

6-keto Prostaglandin F1α-d4 (6-keto PGF1α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions.

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6-keto Prostaglandin F1α-d4 التركيب الكيميائي

Cas No.: 82414-64-0

الحجم السعر المخزون الكميّة
25μg
105٫00
متوفر
50μg
199٫00
متوفر
100μg
356٫00
متوفر
1mg
2589٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of 6-keto Prostaglandin F1α-d4

6-keto Prostaglandin F1α-d4 (6-keto PGF1α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1α by GC- or LC-MS. 6-keto PGF1α is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF1α serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1α.

Chemical Properties of 6-keto Prostaglandin F1α-d4

Cas No. 82414-64-0 SDF
المرادفات 6keto PGF1αd4
Chemical Name 6-oxo-9α,11α,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Canonical SMILES O[C@@H]1[C@H](CC(CC([2H])([2H])C([2H])([2H])CC(O)=O)=O)[C@@H](/C=C/[C@H](O)CCCCC)[C@H](O)C1
Formula C20H30D4O6 M.Wt 374.5
الذوبان DMF: >100 mg/ml (from 6-keto PGF1a),DMSO: >50 mg/ml (from 6-keto PGF1a),Ethanol: >16 mg/ml (from 6-keto PGF1a),PBS pH 7.2: >3.3 mg/ml (from 6-keto PGF1a Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 6-keto Prostaglandin F1α-d4

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6702 mL 13.3511 mL 26.7023 mL
5 mM 534 μL 2.6702 mL 5.3405 mL
10 mM 267 μL 1.3351 mL 2.6702 mL
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In vivo Formulation Calculator (Clear solution) of 6-keto Prostaglandin F1α-d4

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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