الصفحة الرئيسية>>Signaling Pathways>> GPCR/G protein>> CRFR>>α-Helical CRF(9-41) TFA

α-Helical CRF(9-41) TFA

رقم الكتالوجGC66088

α ؛ -Helical CRF (9-41) TFA هو مضاد لمستقبل CRF2 تنافسي مع كيلوبايت من ~ 100 نانومتر. α ؛ -Helical CRF (9-41) TFA هو أيضًا ناهض جزئي لمستقبل CRF1 مع EC50 من 140 نانومتر.

Products are for research use only. Not for human use. We do not sell to patients.

α-Helical CRF(9-41) TFA التركيب الكيميائي

الحجم السعر المخزون الكميّة
1mg
360٫00
متوفر
5mg
1080٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description of α-Helical CRF(9-41) TFA

α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) TFA is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2].

Chemical Properties of α-Helical CRF(9-41) TFA

Cas No. SDF
Formula C168H275F3N46O55S2 M.Wt 3940.42
الذوبان H2O : 1.82 mg/mL (0.46 mM; ultrasonic and adjust pH to 3 with HCl) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of α-Helical CRF(9-41) TFA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.2538 mL 1.2689 mL 2.5378 mL
5 mM 0.0508 mL 0.2538 mL 0.5076 mL
10 mM 0.0254 mL 0.1269 mL 0.2538 mL
  • حاسبة المولارية

  • حاسبة التخفيف

  • Molecular Weight Calculator

كتلة
=
تركيز
x
مقدار
x
ميغاواط *
 
 
 
** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

احسب

In vivo Formulation Calculator (Clear solution) of α-Helical CRF(9-41) TFA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

مراجعات

Review for α-Helical CRF(9-41) TFA

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for α-Helical CRF(9-41) TFA

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.