Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) (Synonyms: Adrenic Acid) |
| رقم الكتالوجGC31602 |
حمض الأدرينيك (cis-7،10،13،16-دوكوساتتراينويك أسيد) هو حمض دهني متعدد غير مشبع بطبيعته يتواجد في الغدة الكظرية والمخ والكلى والأوعية الدموية.
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Cas No.: 28874-58-0
Sample solution is provided at 25 µL, 10mM.
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7Z,10Z,13Z,16Z-Docosatetraenoic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-carbon chain elongation of arachidonic acid. It is present in the adrenal glands, brain, testis, and kidney.[1] Although there is trace metabolism of adrenic acid in the forebrain, the renal medulla is the only tissue which readily metabolizes the acid through cyclooxygenase activity.[1],[2] The primary metabolite of 7Z,10Z,13Z,16Z-docosatetraenoic acid in the rabbit kidney is 1a,1b-dihomo prostaglandin E2.[1]
Reference:
[1]. Sprecher, H., VanRollins, M., Sun, F., et al. Dihomo-prostaglandins and -thromboxane. A prostaglandin family from adrenic acid that may be preferentially synthesized in the kidney. The Journal of Biological Chemisty 257, 3912-3918 (1982).
[2]. Ferretti, A., and Flanagan, V.P. Mass spectrometric evidence for the conversion of exogenous adrenate to dihomo-prostaglandins by seminal vesicle cyclo-oxygenase. A comparative study of two animal species. Journal of Chromatography 383, 241-250 (1986).
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