Adrenomedullin (AM) (1-52), human (Synonyms: Human adrenomedullin-(1-52)-NH2) |
| رقم الكتالوجGC33955 |
Adrenomedullin (AM) (1-52) ، الإنسان عبارة عن ببتيد مكون من 52 حمض أميني ، والذي يؤثر على تكاثر الخلايا وتكوين الأوعية في السرطان.
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Cas No.: 148498-78-6
Sample solution is provided at 25 µL, 10mM.
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Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer.
To explore the effect of Adrenomedullin (AM) (1-52), human on astroglioma cells, CRT-MG cells are incubated in the absence or presence of Adrenomedullin (AM) (1-52), human (ADM1-52) for 48 h in a medium containing 1% FBS, and wound-healing assay is performed. The number of cells migrating to the wound region significantly increases in the ADM1-52-treated cells, in a dose-dependent manner, compared to the untreated cells[1].
[1]. Lim SY, et al. Transcriptional regulation of adrenomedullin by oncostatin M in human astroglioma cells: implications for tumor invasion and migration. Sci Rep. 2014 Sep 23;4:6444.
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