ADTL-SA1215 |
رقم الكتالوجGC64527 |
ADTL-SA1215 هو المنشط الجزيئي الصغير الأول في فئته من SIRT3 الذي ينظم الالتهام الذاتي في سرطان الثدي السلبي الثلاثي.
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Cas No.: 782387-91-1
Sample solution is provided at 25 µL, 10mM.
ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer.
[1]. Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216.
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