Atorvastatin lactone |
| رقم الكتالوجGC42868 |
أتورفاستاتين لاكتون هو أحد أشكال الأدوية الأولية من أتورفاستاتين
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Cas No.: 125995-03-1
Sample solution is provided at 25 µL, 10mM.
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Atorvastatin lactone is a prodrug form of atorvastatin , an HMG-CoA reductase inhibitor used to lower blood cholesterol levels. The lactone hydrolyzes rapidly to the acid form of atorvastatin in human serum at room temperature. Atorvastatin lactone can also be formed in vivo from atorvastatin by certain uridine 5'-diphospho-glucuronosyltransferases. Like atorvastatin, the lactone inhibits P-glycoprotein in a concentration-dependent manner.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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