AZA1 (Synonyms: Rac1/Cdc42-IN-1) |
| رقم الكتالوجGC39817 |
AZA1 هو مثبط مزدوج قوي لـ Rac1 و Cdc42يحفز AZA1 موت الخلايا المبرمج لخلايا سرطان البروستاتا ويمنع تكاثر خلايا سرطان البروستاتا وهجرتها وغزوها
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1071098-42-4
Sample solution is provided at 25 µL, 10mM.
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AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion[1][2].
[1]. Zins K, et al. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice. PLoS One. 2013;8(9):e74924. Published 2013 Sep 11. [2]. Suzuki O, et al. Sialylation and glycosylation modulate cell adhesion and invasion to extracellular matrix in human malignant lymphoma: Dependency on integrin and the Rho GTPase family. Int J Oncol. 2015;47(6):2091‐2099.
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