BI-3812 |
| رقم الكتالوجGC32990 |
BI-3812 هو مثبط BCL6 قوي وفعال ، يثبط مجال BTB لـ BCL6 ، مع IC50 من ≤3 نانومتر ؛ BI-3812 له نشاط مضاد للأورام
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Cas No.: 2166387-64-8
Sample solution is provided at 25 µL, 10mM.
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BI-3812 is potent and efficacious BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM; BI-3812 has antitumor activity.
BI-3812 is a BCL6 inhibitor, with an IC50 of ≤3 nM. BI-3812 shows an IC50 of 40 nM for the cellular BCL6[1].
[1]. Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20(12):2860-2875.
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