PF-06649751 (Synonyms: CVL-751) |
| رقم الكتالوجGC48598 |
PF-06649751 (PF-06649751) هو ناهض جزئي لمستقبل الدوبامين D1 / D5 النشط عن طريق الفم وانتقائي للغاية.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1643489-24-0
Sample solution is provided at 25 µL, 10mM.
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PF-06649751 is a dopamine D1 and D5 receptor partial agonist.1 It increases locomotor activity and reduces a global parkinsonian disability score in a macaque model of Parkinson's disease induced by MPTP when administered at a dose of 0.04 mg/kg.
1.Young, D., Popiolek, M., Trapa, P., et al.D1 agonist improved movement of parkinsonian nonhuman primates with limited dyskinesia side effectsACS Chem. Neurosci.11(4)560-566(2020)
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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