PK150 |
| رقم الكتالوجGC39300 |
يُظهر PK150 ، وهو نظير لـ Sorafenib ، التوافر البيولوجي عن طريق الفم والنشاط المضاد للبكتيريا ضد العديد من السلالات المسببة للأمراض بتركيزات دون المولية
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2165324-62-7
Sample solution is provided at 25 µL, 10mM.
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PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively[1].
[1]. Le P, et al. Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. Nat Chem. 2019 Dec 16.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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