O-glycosylation-IN-1 (Synonyms: Benzyl N-acetyl-α-D-galactosaminide, Benzyl-α-GalNAc) |
| رقم الكتالوجGC39720 |
O-glycosylation-IN-1 هو أحد مثبطات O-glycosylation القوية ويستخدم لتقليل الميوسين على أسطح الخلايا. يثبط ارتباط O-glycosylation-IN-1 تخليق mucin O-glycosylation للنماذج الخلوية لسرطان البنكرياس البشري.
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Cas No.: 3554-93-6
Sample solution is provided at 25 µL, 10mM.
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O-glycosylation-IN-1 is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. O-glycosylation-IN-1 inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1].
[1]. Kalra AV, et al. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer. 2007 Oct 8;97(7):910-8. Epub 2007 Oct 2.
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