2-Hydroxy atorvastatin lactone |
رقم الكتالوجGC60474 |
2-هيدروكسي أتورفاستاتين لاكتون هو مستقلب أتورفاستاتين
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Cas No.: 163217-74-1
Sample solution is provided at 25 µL, 10mM.
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
[1]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790. [2]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol. 2007 Oct;50(4):458-61.
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