14-dehydro Zymostenol (Synonyms: Δ8,14-Cholestandienol, Cholesta-8,14-dien-3β-ol) |
رقم الكتالوجGC46437 |
A cholesterol precursor
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Cas No.: 19431-20-0
Sample solution is provided at 25 µL, 10mM.
14-dehydro Zymostenol is a precursor to cholesterol .1 It increases the percentage of myelin basic protein-positive (MBP+) oligodendrocytes formed from oligodendrocyte precursor cells when used at concentrations of 5.8 and 17 µM.2
1.Lutsky, B.N., and Schroepfer, G.J., Jr.Studies on the enzymic conversion of 5α-cholesta-8,14-dien-3β-ol to cholesterolJ. Biol. Chem.245(23)6449-6455(1970) 2.Hubler, Z., Allimuthu, D., Bederman, I., et al.Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelinationNature560(7718)372-376(2018)
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