Eltenac |
| رقم الكتالوجGC47287 |
Eltenac ، عقار مضاد للالتهابات غير ستيرويدي (NSAID) ، هو مثبط لـ COX
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 72895-88-6
Sample solution is provided at 25 µL, 10mM.
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Eltenac is a non-selective COX inhibitor (IC50 = 0.03 µM for both COX-1 and COX-2 in isolated human whole blood) and a non-steroidal anti-inflammatory drug (NSAID).1 In vivo, eltenac (1 mg/kg) reduces lameness in horses with tendinitis, pododermatitis, navicular disease, non-infectious arthritis, degenerative joint disease, phalanx fracture, and osteochondrosis.2 It also reduces castration-induced edema in horses. Formulations containing eltenac have been used in the treatment of postoperative swelling in horses.
1.Klein, T., Dullweber, F., Brehm, C., et al.Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivoBiochem. Pharmacol.76(6)717-725(2008) 2.PrÜgner, W., Huber, R., and LÜhmann, R.Eltenac, a new anti-inflammatory and analgesic drug for horses: clinical aspectsJ. Vet. Pharmacol. Ther.14(2)193-199(1991)
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