Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Synonyms: CMIT/MIT, MCI/MI, MCIT/MIT)

Name: Methylchloroisothiazolinone/Methylisothiazolinone Mixture
Brand: GlpBio
SKU: GC48857
Availability: InStock
Rating: 5 (38 reviews)

رقم الكتالوجGC48857

A mixture of isothiazolinone biocides

Products are for research use only. Not for human use. We do not sell to patients.

Methylchloroisothiazolinone/Methylisothiazolinone Mixture التركيب الكيميائي

Cas No.: 55965-84-9

الحجم

السعر

المخزون

الكميّة

5mL	55٫00	متوفر
10mL	98٫00	متوفر
25mL	207٫00	متوفر
100mL	494٫00	متوفر

Tel：(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.

منتجات GlpBio المذكورة في الأوراق ذات السمعة الطيبة

Nature
610.7931 (2022): 366-372

Nature
618, 1017–1023 (2023)

Cell
183.7 (2020): 1867-1883

Cell Research
31, 1291–1307 (2021)

Cell Research
33, 273–287 (2023)

Cell Research
33, 546–561 (2023)

Molecular Cancer
21.1 (2022): 1-17

Molecular Cancer
21.1 (2022): 1-18

Cancer Cell
39 (2021): 1-16

Cell Host Microbe
30.8 (2022): 1124-1138

Cell Host Microbe
31.5 (2023): 766-780

Cell Host Microbe
31.3 (2023): 418-43

Cell Metabolism
34.2 (2022): 240-255

Ann Rheum Dis
82(4): 533-545 (2023)

Cell Mol Immunol
20, 264–276 (2023)

Adv Funct Mater
33.35 (2023): 2214998

Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >98.00%

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.^1,2 It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively.² MCIT/MIT can elicit contact sensitization.³ Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products.

1.Frenzel, E., Schmidt, S., Niederweis, M., et al.Importance of porins for biocide efficacy against Mycobacterium smegmatisApplied and Environmental Microbiology77(9)3068-3073(2011) 2.Lundov, M.D., Johansen, J.D., Zachariae, C., et al.Low-level efficacy of cosmetic preservativesInt. J. Cosmet. Sci.33(2)190-196(2011) 3.Scherrer, M.A.R., and Rocha, V.B.Increasing trend of sensitization to methylchloroisothiazolinone/methylisothiazolinone (MCI/MI)An. Bras. Dermatol.89(3)527-528(2014)

Cas No.	55965-84-9	SDF
المرادفات	CMIT/MIT, MCI/MI, MCIT/MIT
Canonical SMILES	CN(SC(Cl)=C1)C1=O.CN(SC=C2)C2=O
Formula	C4H5NOS•C4H4ClNOS	M.Wt	264.7
الذوبان		Storage	-20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	3.7779 mL	18.8893 mL	37.7786 mL
	5 mM	0.7556 mL	3.7779 mL	7.5557 mL
	10 mM	0.3778 mL	1.8889 mL	3.7779 mL

حاسبة المولارية
حاسبة التخفيف

احسب

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

مراجعات

Review for Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

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Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Synonyms: CMIT/MIT, MCI/MI, MCIT/MIT)

مراجعات العميل

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