Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) (Synonyms: Cav-1, Caveolin-1 Scaffolding Domain Peptide, CSD, CSP, DGIWKASFTTFTVTKYWFYR-NH2) |
| رقم الكتالوجGC52389 |
A synthetic peptide fragment of caveolin-1
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Caveolin-1 (82-101) amide is a 20-amino acid synthetic peptide fragment corresponding to residues 82-101 of caveolin-1, which is involved in endocytosis and interacts with a variety of receptors and other proteins.1 Caveolin-1 (82-101) (0.8 µmol/kg) reduces aging-induced increases in microvascular leakage and fibrosis, as well as the ratio of phosphorylated-to-unphosphorylated PDGFR and protein-rich tyrosine 2 (Pyk2), in aged mouse heart, kidney, and brain. It also increases left ventricular ejection fraction and fractional shortening and reduces aging-induced isovolumic relaxation time (IVRT) and cardiac hypertrophy in aged mice.
1.Kuppuswamy, D., Chinnakkannu, P., Reese, C., et al.The caveolin-1 scaffolding domain peptide reverses aging-associated deleterious changes in multiple organsJ. Pharmacol. Exp. Ther.378(1)1-9(2021)
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