الصفحة الرئيسية>>Cefcanel daloxate HCl

Cefcanel daloxate HCl (Synonyms: Cefcanel daloxate hydrochloride; Cefcanel daloxate HCl; KY-109; KY109; KY 109;)

رقم الكتالوجGB62313 Copy One-Click Copy Product Info

Cefcanel daloxate, also known as KY-109, is a pro-drug to improve oral absorption of KY-087.

Products are for research use only. Not for human use. We do not sell to patients.

Cefcanel daloxate HCl التركيب الكيميائي

Cas No.: 92602-21-6

الحجم السعر المخزون الكميّة
1mg
150٫00
متوفر
5mg
550٫00
متوفر
10mg
950٫00
متوفر
25mg
1850٫00
متوفر
50mg
2950٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Cefcanel daloxate HCl

Cefcanel daloxate, also known as KY-109, is a pro-drug to improve oral absorption of KY-087. The antimicrobial activities of KY-087 against clinically isolated Gram-positive organisms were superior to those of CEX and CCL. The antimicrobial activities of KY-087 against Gram-negative organisms, such as Enterobacter sp., Serratia, and Pseudomonas sp., were less active. KY-087 showed dose-related bactericidal activity against Staphylococcus aureus and Escherichia coli. The therapeutic efficacy of KY-109 against experimental intraperitoneal infections caused by Gram-positive and Gram-negative organisms in mice was comparable to that of CEX but inferior to that of CCL. In experimental granuloma pouch models in rats and kidney infection in rabbits, therapeutic efficacy of KY-109 was either comparable or superior to that of CEX and CCL.

Chemical Properties of Cefcanel daloxate HCl

Cas No. 92602-21-6 SDF
المرادفات Cefcanel daloxate hydrochloride; Cefcanel daloxate HCl; KY-109; KY109; KY 109;
Canonical SMILES O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC([C@H](OC([C@H](C)N)=O)C4=CC=CC=C4)=O)C1=O)OCC5=C(C)OC(O5)=O.[H]Cl
Formula C27H28ClN5O9S3 M.Wt 698.18
الذوبان Soluble in DMSO Storage Store at-20℃
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cefcanel daloxate HCl

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.4323 mL 7.1615 mL 14.323 mL
5 mM 286.5 μL 1.4323 mL 2.8646 mL
10 mM 143.2 μL 716.1 μL 1.4323 mL
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In vivo Formulation Calculator (Clear solution) of Cefcanel daloxate HCl

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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