Cefditoren Pivoxil (Synonyms: ME1207) |
رقم الكتالوجGC18036 |
سيفديتورين بيفوكسيل (ME 1207) هو مضاد للجراثيم واسع الطيف من الجيل الثالث من السيفالوسبورين عن طريق الفم مع ثبات محسّن ضد العديد من إنزيمات اللاكتاماز الشائعة.
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Cas No.: 117467-28-4
Sample solution is provided at 25 µL, 10mM.
Cefditoren pivoxil is a new-third generation cephalosporin antibiotic that has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including common respiratory and skin pathogens.Target: AntibacterialCefditoren pivoxil, a new-third generation cephalosporin antibiotic that has recently been granted approval in Spain, shows important activity over a large part of the pathogens causing skin, soft tissue and respiratory tract infections, including Gram-negative and Gram-positive bacteria. Cefditoren is also marketed under the name Meiact. Cefditoren has a broad spectrum of activity and has been used to treat bacterial infections of the skin and respiratory tract including bronchitis, pneumonia, and tonsillitis. The following represents MIC susceptibility data for a few medically significant microorganisms.Cefditoren has shown excellent in vitro activity against the Gram-positive pathogens penicillin-susceptible and -intermediate Streptococcus pneumoniae, S. pyogenes and methicillin-susceptible Staphylococcus aureus. Cefditoren was inactive against methicillin-resistant S. aureus. Of the important Gram-negative pathogens, cefditoren had potent antibacterial effects against beta-lactamase-positive and -negative Haemophilus influenzae, H. parainfluenzae and beta-lactamase-positive and -negative Moraxella catarrhalis.
References:
[1]. Hernández-Martin J, et al. Cefditoren pivoxil: A new oral cephalosporin for skin, soft tissue and respiratory tract infections. Rev Esp Quimioter. 2006 Sep;19(3):231-46.
[2]. Darkes MJ, et al. Cefditoren pivoxil. Drugs. 2002;62(2):319-36; discussion 337-8.
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