Cyclo(RGDfC) (trifluoroacetate salt) (Synonyms: c(RGDfC), cyclo(Arg-Gly-Asp-D-Phe-Cys)) |
| رقم الكتالوجGC49707 |
A cyclic pentapeptide
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Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Cyclo(RGDfC) is a cyclic pentapeptide that contains the αVβ3 integrin-binding sequence arginine-glycine-aspartate (RGD).1,2 It has been used in the synthesis of unimolecular micelles and ligand-decorated nanogels for cancer cell-targeted drug delivery.
1.Ryu, J.-H., Bickerton, S., Zhuang, J., et al.Ligand-decorated nanogels: Fast one-pot synthesis and cellular targetingBiomacromolecules13(5)1515-1522(2012) 2.Xiao, Y., Hong, H., Javadi, A., et al.Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imagingBiomaterials33(11)3071-3082(2012)
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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